InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Protein: DDO

Summary

InnateDB Protein

IDBP-95249.7

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

DDO

Protein Name

D-aspartate oxidase

Synonyms

DASOX; DDO-1; DDO-2;

Species

Homo sapiens

Ensembl Protein

ENSP00000357919

InnateDB Gene

IDBG-95243 (DDO)

Protein Structure

UniProt Annotation

Function

Selectively catalyzes the oxidative deamination of D- aspartate and its N-methylated derivative, N-methyl D-aspartate.

Subcellular Localization

Peroxisome.

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 3 experimentally validated interaction(s) in this database.

Experimentally validated
Total	3 [view]
Protein-Protein	3 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Gene Ontology

Molecular Function

Accession	GO Term
GO:0005102	receptor binding
GO:0005515	protein binding
GO:0008445	D-aspartate oxidase activity
GO:0016491	oxidoreductase activity
GO:0048037	cofactor binding

Biological Process

GO:0006533	aspartate catabolic process
GO:0019478	D-amino acid catabolic process
GO:0055114	oxidation-reduction process

Cellular Component

GO:0005777

peroxisome

Protein Structure and Domains

PDB ID

InterPro

IPR006076 FAD dependent oxidoreductase

PFAM

PF01266

PRINTS

PIRSF

SMART

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

Q99489

PhosphoSite

PhosphoSite-Q99489

TrEMBL

UniProt Splice Variant

Entrez Gene

8528

UniGene

Hs.591348

RefSeq

NP_004023

HUGO

HGNC:2727

OMIM

124450

CCDS

CCDS5083

HPRD

00498

IMGT

EMBL

AK293029 AL050350 BC032786 CH471051 D89858 DN990727

GenPept

AAH32786 BAA14031 BAF85718 CAI42509 CAI42510 CAI42511 EAW48316 EAW48317