InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Protein: SLC18A1

Summary

InnateDB Protein

IDBP-9670.5

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

SLC18A1

Protein Name

solute carrier family 18 (vesicular monoamine), member 1

Synonyms

CGAT; VAT1; VMAT1;

Species

Homo sapiens

Ensembl Protein

ENSP00000371021

InnateDB Gene

IDBG-9668 (SLC18A1)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 3 experimentally validated interaction(s) in this database.

Experimentally validated
Total	3 [view]
Protein-Protein	0
Protein-DNA	1 [view]
Protein-RNA	0
DNA-DNA	2 [view]
RNA-RNA	0
DNA-RNA	0

Gene Ontology

Molecular Function

Accession	GO Term
GO:0008504	monoamine transmembrane transporter activity
GO:0015238	drug transmembrane transporter activity

Biological Process

GO:0006836	neurotransmitter transport
GO:0006855	drug transmembrane transport
GO:0015844	monoamine transport
GO:0015893	drug transport
GO:0055085	transmembrane transport

Cellular Component

GO:0005789	endoplasmic reticulum membrane
GO:0016021	integral component of membrane
GO:0070083	clathrin-sculpted monoamine transport vesicle membrane

Protein Structure and Domains

PDB ID

InterPro

IPR004734 Multidrug resistance protein
IPR011701 Major facilitator superfamily
IPR016196 Major facilitator superfamily domain, general substrate transporter
IPR020846 Major facilitator superfamily domain

PFAM

PF07690

PRINTS

PIRSF

SMART

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

P54219

PhosphoSite