InnateDB Protein
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IDBP-96810.6
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Last Modified
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2014-10-13 [Report errors or provide feedback]
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Gene Symbol
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ALDH8A1
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Protein Name
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aldehyde dehydrogenase 8 family, member A1
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Synonyms
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Species
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Homo sapiens
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Ensembl Protein
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ENSP00000265605
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InnateDB Gene
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IDBG-96808 (ALDH8A1)
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Protein Structure
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Function |
Converts 9-cis-retinal to 9-cis-retinoic acid. Has lower activity towards 13-cis-retinal. Has much lower activity towards all-trans-retinal. Has highest activity with benzaldehyde and decanal (in vitro). Has a preference for NAD, but shows considerable activity with NADP (in vitro). {ECO:0000269PubMed:11007799}.
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Subcellular Localization |
Cytoplasm {ECO:0000250}.
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Disease Associations |
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Tissue Specificity |
Highly expressed in adult kidney and liver. Detected at lower levels in fetal liver and kidney. {ECO:0000269PubMed:11007799}.
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Comments |
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Number of Interactions
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This gene and/or its encoded proteins are associated with 3 experimentally validated interaction(s) in this database.
Experimentally validated |
Total |
3
[view]
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Protein-Protein |
1
[view]
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Protein-DNA |
2
[view]
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Protein-RNA |
0
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DNA-DNA |
0
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RNA-RNA |
0
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DNA-RNA |
0
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Molecular Function |
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Biological Process |
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Cellular Component |
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PDB ID |
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InterPro |
IPR015590
Aldehyde dehydrogenase domain
IPR016161
Aldehyde/histidinol dehydrogenase
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PFAM |
PF00171
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PRINTS |
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PIRSF |
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SMART |
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TIGRFAMs |
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Modification |
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SwissProt |
Q9H2A2
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PhosphoSite |
PhosphoSite-Q9H2A2
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TrEMBL |
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UniProt Splice Variant |
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Entrez Gene |
64577
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UniGene |
Hs.486520
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RefSeq |
NP_072090
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HUGO |
HGNC:15471
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OMIM |
606467
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CCDS |
CCDS5171
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HPRD |
06974
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IMGT |
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EMBL |
AF303134
AK222848
AK290784
AK298325
AL021939
AL445190
BC113862
BC114473
CH471051
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GenPept |
AAG42417
AAI13863
AAI14474
BAD96568
BAF83473
BAH12757
CAI20305
CAI20306
CAI95158
CAI95159
EAW47985
EAW47986
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