Version 5.4
Homo sapiens Protein: ATP6V0B
Summary
InnateDB Protein IDBP-97635.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol ATP6V0B
Protein Name ATPase, H+ transporting, lysosomal 21kDa, V0 subunit b
Synonyms ATP6F; HATPL; VMA16;
Species Homo sapiens
Ensembl Protein ENSP00000236067
InnateDB Gene IDBG-97633 (ATP6V0B)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 6 experimentally validated interaction(s) in this database.
Experimentally validated
Total 6 [view]
Protein-Protein 6 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0005215 transporter activity
GO:0015078 hydrogen ion transmembrane transporter activity
Biological Process
GO:0006879 cellular iron ion homeostasis
GO:0008286 insulin receptor signaling pathway
GO:0015991 ATP hydrolysis coupled proton transport
GO:0015992 proton transport
GO:0033572 transferrin transport
GO:0051701 interaction with host
GO:0055085 transmembrane transport
GO:0090382 phagosome maturation
Cellular Component
GO:0005774 vacuolar membrane
GO:0010008 endosome membrane
GO:0030670 phagocytic vesicle membrane
GO:0033177 proton-transporting two-sector ATPase complex, proton-transporting domain
GO:0033179 proton-transporting V-type ATPase, V0 domain
Protein Structure and Domains
PDB ID
InterPro IPR000245 V-ATPase proteolipid subunit
IPR002379 V-ATPase proteolipid subunit C-like domain
PFAM PF00137
PRINTS PR00122
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q99437
PhosphoSite PhosphoSite-Q99437
TrEMBL E9PMR1
UniProt Splice Variant
Entrez Gene 533
UniGene
RefSeq NP_001034546
HUGO HGNC:861
OMIM 603717
CCDS CCDS41315
HPRD 04759
IMGT
EMBL AL357079 BC000423 BC005876 BT007151 CH471059 CR456972 D89052
GenPept AAH00423 AAH05876 AAP35815 BAA13753 CAG33253 CAI16801 EAX07066 EAX07067 EAX07068

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca