Homo sapiens Protein: SYNJ2
Summary
InnateDB Protein IDBP-98403.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol SYNJ2
Protein Name synaptojanin 2
Synonyms INPP5H;
Species Homo sapiens
Ensembl Protein ENSP00000356079
InnateDB Gene IDBG-98393 (SYNJ2)
Protein Structure
UniProt Annotation
Function Inositol 5-phosphatase which may be involved in distinct membrane trafficking and signal transduction pathways. May mediate the inhibitory effect of Rac1 on endocytosis.
Subcellular Localization Membrane {ECO:0000250}. Note=Predominantly associated with the particulate fractions. {ECO:0000250}.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 13 experimentally validated interaction(s) in this database.
Experimentally validated
Total 13 [view]
Protein-Protein 13 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0000166 nucleotide binding
GO:0003676 nucleic acid binding
Biological Process
Cellular Component
Protein Structure and Domains
PDB ID
InterPro IPR000504 RNA recognition motif domain
IPR015047 Domain of unknown function DUF1866
PFAM PF00076
PF08952
PRINTS
PIRSF
SMART SM00360
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt
PhosphoSite PhosphoSite-O15056
TrEMBL X6R647
UniProt Splice Variant
Entrez Gene 8871
UniGene Hs.707706
RefSeq
HUGO HGNC:11504
OMIM 609410
CCDS
HPRD 10259
IMGT
EMBL AL139330
GenPept