Version 5.4
Homo sapiens Protein: SSBP3
Summary
InnateDB Protein IDBP-98978.7
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol SSBP3
Protein Name single stranded DNA binding protein 3
Synonyms CSDP; SSDP; SSDP1;
Species Homo sapiens
Ensembl Protein ENSP00000360370
InnateDB Gene IDBG-98972 (SSBP3)
Protein Structure
UniProt Annotation
Function May be involved in transcription regulation of the alpha 2(I) collagen gene where it binds to the single-stranded polypyrimidine sequences in the promoter region. {ECO:0000250}.
Subcellular Localization Nucleus {ECO:0000250}.
Disease Associations
Tissue Specificity Highly expressed in all hematopoietic tissues, including spleen, lymph node, peripheral blood, bone marrow, thymus, and fetal liver, with highest expression in thymus and fetal liver. Expression is also high in heart, brain, kidney, and skeletal muscle.
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 15 experimentally validated interaction(s) in this database.
They are also associated with 29 interaction(s) predicted by orthology.
Experimentally validated
Total 15 [view]
Protein-Protein 15 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 29 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003697 single-stranded DNA binding
GO:0005515 protein binding
Biological Process
GO:0006351 transcription, DNA-templated
Cellular Component
GO:0005634 nucleus
Protein Structure and Domains
PDB ID
InterPro IPR006594 LisH dimerisation motif
IPR008116 Sequence-specific single-strand DNA-binding protein
PFAM
PRINTS PR01743
PIRSF
SMART SM00667
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q9BWW4
PhosphoSite PhosphoSite-Q9BWW4
TrEMBL Q9BT57
UniProt Splice Variant
Entrez Gene 23648
UniGene Hs.733025
RefSeq NP_001009955
HUGO HGNC:15674
OMIM 607390
CCDS CCDS30726
HPRD 09578
IMGT
EMBL AF500116 AK289474 AL035415 AL161644 AL354778 AY026293 AY026294 AY026295 AY026296 AY026297 AY026298 AY026299 AY026300 AY026301 AY026302 AY026303 AY026304 AY026305 AY026306 AY026307 AY026308 AY026309 AY026310 BC003605 BC004335 BC066365 CH471059
GenPept AAH03605 AAH04335 AAH66365 AAK21984 AAK21985 AAM22101 BAF82163 CAI22487 CAI22488 CAI23562 CAI23563 EAX06692

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca