Homo sapiens Gene: SLC30A7
Summary
InnateDB Gene IDBG-100539.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol SLC30A7
Gene Name solute carrier family 30 (zinc transporter), member 7
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000162695
Encoded Proteins
solute carrier family 30 (zinc transporter), member 7
solute carrier family 30 (zinc transporter), member 7
solute carrier family 30 (zinc transporter), member 7
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary Zinc functions as a cofactor for numerous enzymes, nuclear factors, and hormones and as an intra- and intercellular signal ion. Members of the zinc transporter (ZNT)/SLC30 subfamily of the cation diffusion facilitator family, such as SLC30A7, permit cellular efflux of zinc (Seve et al., 2004 [PubMed 15154973]).[supplied by OMIM, Mar 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 1:100896076-100981753
Strand Forward strand
Band p21.2
Transcripts
ENST00000370112 ENSP00000359130
ENST00000370111 ENSP00000359129
ENST00000357650 ENSP00000350278
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 5 experimentally validated interaction(s) in this database.
Experimentally validated
Total 5 [view]
Protein-Protein 4 [view]
Protein-DNA 1 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0008324 cation transmembrane transporter activity
Biological Process
GO:0006812 cation transport
GO:0006829 zinc ion transport
GO:0032119 sequestering of zinc ion
GO:0044267 cellular protein metabolic process
GO:0055085 transmembrane transport
Cellular Component
GO:0000139 Golgi membrane
GO:0005737 cytoplasm
GO:0005794 Golgi apparatus
GO:0016021 integral component of membrane
GO:0016023 cytoplasmic membrane-bounded vesicle
GO:0031982 vesicle
GO:0048471 perinuclear region of cytoplasm
GO:0070062 extracellular vesicular exosome
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
Not yet available
Pathways
NETPATH
REACTOME
Zinc efflux and compartmentalization by the SLC30 family pathway
Metal ion SLC transporters pathway
Transport of glucose and other sugars, bile salts and organic acids, metal ions and amine compounds pathway
Insulin processing pathway
Transmembrane transport of small molecules pathway
Metabolism of proteins pathway
Zinc transporters pathway
Peptide hormone metabolism pathway
SLC-mediated transmembrane transport pathway
KEGG
INOH
PID NCI
Cross-References
SwissProt Q8NEW0
TrEMBL
UniProt Splice Variant
Entrez Gene 148867
UniGene Hs.606496 Hs.619680
RefSeq NM_001144884 NM_133496 XM_005270503
HUGO HGNC:19306
OMIM 611149
CCDS CCDS776
HPRD 15369
IMGT
EMBL AC104506 AF233345 AF529197 AK313638 AL732465 AY094606 BC064692 BX537375 CH471097
GenPept AAH64692 AAL83716 AAM21969 AAO17324 BAG36396 CAD97617 CAI13301 EAW72942 EAW72943
RNA Seq Atlas 148867