Homo sapiens Gene: FCRL3
Summary
InnateDB Gene IDBG-103681.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol FCRL3
Gene Name Fc receptor-like 3
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000160856
Encoded Proteins
Fc receptor-like 3
Fc receptor-like 3
Fc receptor-like 3
Fc receptor-like 3
Fc receptor-like 3
Fc receptor-like 3
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene encodes a member of the immunoglobulin receptor superfamily and is one of several Fc receptor-like glycoproteins clustered on the long arm of chromosome 1. The encoded protein contains immunoreceptor-tyrosine activation motifs and immunoreceptor-tyrosine inhibitory motifs in its cytoplasmic domain and may play a role in regulation of the immune system. Mutations in this gene have been associated with rheumatoid arthritis, autoimmune thyroid disease, and systemic lupus erythematosus. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 1:157674321-157700857
Strand Reverse strand
Band q23.1
Transcripts
ENST00000368186 ENSP00000357169
ENST00000368184 ENSP00000357167
ENST00000485028 ENSP00000434331
ENST00000477837 ENSP00000433430
ENST00000492769 ENSP00000435487
ENST00000480682
ENST00000494724
ENST00000473231
ENST00000468507
ENST00000478179
ENST00000496769 ENSP00000473680
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 5 experimentally validated interaction(s) in this database.
Experimentally validated
Total 5 [view]
Protein-Protein 5 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
Biological Process
Cellular Component
GO:0005886 plasma membrane
GO:0016021 integral component of membrane
Orthologs
No orthologs found for this gene
Pathways
NETPATH
TCR pathway
REACTOME
KEGG
INOH
PID NCI
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Hs.292449 Hs.609636 Hs.610271 Hs.733831
RefSeq NM_052939 XM_006711145 XM_006711146 XM_006711147
HUGO
OMIM
CCDS CCDS1167
HPRD 07352
IMGT
EMBL
GenPept
RNA Seq Atlas