Version 5.4
Homo sapiens Gene: UAP1
Summary
InnateDB Gene IDBG-104387.5
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol UAP1
Gene Name UDP-N-acteylglucosamine pyrophosphorylase 1
Synonyms AGX; AGX1; AGX2; SPAG2
Species Homo sapiens
Ensembl Gene ENSG00000117143
Encoded Proteins
IDBP-104389
UDP-N-acteylglucosamine pyrophosphorylase 1
IDBP-104391
UDP-N-acteylglucosamine pyrophosphorylase 1
IDBP-104393
UDP-N-acteylglucosamine pyrophosphorylase 1
IDBP-104395
UDP-N-acteylglucosamine pyrophosphorylase 1
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary Currently no Entrez Summary Available. You might want to check the Summary Sections of the Orthologs.
Gene Information
Type Protein coding
Genomic Location Chromosome 1:162561506-162599842
Strand Forward strand
Band q23.3
Transcripts
ENST00000367926 ENSP00000356903
ENST00000271469 ENSP00000271469
ENST00000367925 ENSP00000356902
ENST00000367924 ENSP00000356901
ENST00000476240
ENST00000474728
ENST00000486089
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 11 experimentally validated interaction(s) in this database.
Experimentally validated
Total 11 [view]
Protein-Protein 11 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0003977 UDP-N-acetylglucosamine diphosphorylase activity
GO:0030246 carbohydrate binding
GO:0070569 uridylyltransferase activity
Biological Process
GO:0006047 UDP-N-acetylglucosamine metabolic process
GO:0006048 UDP-N-acetylglucosamine biosynthetic process
GO:0006488 dolichol-linked oligosaccharide biosynthetic process
GO:0008152 metabolic process
GO:0018279 protein N-linked glycosylation via asparagine
GO:0043687 post-translational protein modification
GO:0044267 cellular protein metabolic process
Cellular Component
GO:0005829 cytosol
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000026670
View Gene Order
ENSBTAG00000010206
Not yet available
Pathways
NETPATH
REACTOME
REACT_22394
Synthesis of UDP-N-acetyl-glucosamine pathway
REACT_22433
Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein pathway
REACT_22426
Asparagine N-linked glycosylation pathway
REACT_22161
Post-translational protein modification pathway
REACT_22387
Synthesis of substrates in N-glycan biosythesis pathway
REACT_17015
Metabolism of proteins pathway
KEGG
hsa00520
Amino sugar and nucleotide sugar metabolism pathway
INOH
INOH website
Aminosugars metabolism pathway
PID NCI
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Hs.492859 Hs.598015
RefSeq NM_003115 XM_005245462 XM_005245465
HUGO
OMIM
CCDS CCDS1240
HPRD 04178
IMGT
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca