Version 5.4
Homo sapiens Gene: VAMP4
Summary
InnateDB Gene IDBG-104804.5
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol VAMP4
Gene Name vesicle-associated membrane protein 4
Synonyms VAMP-4; VAMP24
Species Homo sapiens
Ensembl Gene ENSG00000117533
Encoded Proteins
IDBP-104806
vesicle-associated membrane protein 4
IDBP-104808
vesicle-associated membrane protein 4
IDBP-599886
vesicle-associated membrane protein 4
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary Synaptobrevins/VAMPs, syntaxins, and the 25-kD synaptosomal-associated protein SNAP25 are the main components of a protein complex involved in the docking and/or fusion of synaptic vesicles with the presynaptic membrane. The protein encoded by this gene is a member of the vesicle-associated membrane protein (VAMP)/synaptobrevin family. This protein may play a role in trans-Golgi network-to-endosome transport. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 1:171700160-171742247
Strand Reverse strand
Band q24.3
Transcripts
ENST00000367740 ENSP00000356714
ENST00000236192 ENSP00000236192
ENST00000474047 ENSP00000435933
ENST00000482519
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 17 experimentally validated interaction(s) in this database.
Experimentally validated
Total 17 [view]
Protein-Protein 17 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
Biological Process
GO:0016192 vesicle-mediated transport
GO:0035493 SNARE complex assembly
GO:0042996 regulation of Golgi to plasma membrane protein transport
GO:0043001 Golgi to plasma membrane protein transport
Cellular Component
GO:0000139 Golgi membrane
GO:0005764 lysosome
GO:0005768 endosome
GO:0005794 Golgi apparatus
GO:0005802 trans-Golgi network
GO:0009986 cell surface
GO:0016021 integral component of membrane
GO:0031201 SNARE complex
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000026696
View Gene Order
ENSBTAG00000020591
Not yet available
Pathways
NETPATH
REACTOME
KEGG
hsa04130
SNARE interactions in vesicular transport pathway
INOH
PID NCI
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Hs.592778 Hs.599991 Hs.605606 Hs.6651
RefSeq NM_001185127 NM_003762
HUGO
OMIM
CCDS CCDS1298 CCDS53430
HPRD 06070
IMGT
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca