Version 5.4
Mus musculus Gene: Vamp4
Summary
InnateDB Gene IDBG-201827.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Vamp4
Gene Name vesicle-associated membrane protein 4
Synonyms D1Ertd147e
Species Mus musculus
Ensembl Gene ENSMUSG00000026696
Encoded Proteins
IDBP-201831
vesicle-associated membrane protein 4
IDBP-531683
vesicle-associated membrane protein 4
IDBP-535070
vesicle-associated membrane protein 4
IDBP-535483
vesicle-associated membrane protein 4
IDBP-532759
vesicle-associated membrane protein 4
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000117533:
Synaptobrevins/VAMPs, syntaxins, and the 25-kD synaptosomal-associated protein SNAP25 are the main components of a protein complex involved in the docking and/or fusion of synaptic vesicles with the presynaptic membrane. The protein encoded by this gene is a member of the vesicle-associated membrane protein (VAMP)/synaptobrevin family. This protein may play a role in trans-Golgi network-to-endosome transport. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 1:162570515-162599084
Strand Forward strand
Band H2.1
Transcripts
ENSMUST00000050010 ENSMUSP00000051544
ENSMUST00000132158 ENSMUSP00000121977
ENSMUST00000135241 ENSMUSP00000116376
ENSMUST00000128704
ENSMUST00000150040 ENSMUSP00000115133
ENSMUST00000155003 ENSMUSP00000114172
ENSMUST00000138499
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 2 experimentally validated interaction(s) in this database.
They are also associated with 14 interaction(s) predicted by orthology.
Experimentally validated
Total 2 [view]
Protein-Protein 2 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 14 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0000149 SNARE binding
GO:0005484 SNAP receptor activity
Biological Process
GO:0006887 exocytosis
GO:0006897 endocytosis
GO:0006906 vesicle fusion
GO:0016192 vesicle-mediated transport
GO:0035493 SNARE complex assembly
GO:0042996 regulation of Golgi to plasma membrane protein transport
GO:0043001 Golgi to plasma membrane protein transport
Cellular Component
GO:0005794 Golgi apparatus
GO:0005802 trans-Golgi network
GO:0009986 cell surface
GO:0016021 integral component of membrane
GO:0031201 SNARE complex
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000117533
View Gene Order
ENSBTAG00000020591
Not yet available
Pathways
NETPATH
REACTOME
KEGG
mmu04130
SNARE interactions in vesicular transport pathway
INOH
PID NCI
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
KEGG
hsa04130
SNARE interactions in vesicular transport pathway
INOH
PID NCI
Cross-References
SwissProt O70480
TrEMBL Q8BSN6
UniProt Splice Variant
Entrez Gene 53330
UniGene Mm.10699 Mm.396250 Mm.411120
RefSeq NM_016796 XM_006496936
OMIM
CCDS CCDS15421
HPRD
IMGT
MGI ID MGI:1858730
MGI Symbol Vamp4
EMBL AC138218 AF061516 AK011678 AK018344 AK031151 BC138753 BC138754 CH466520
GenPept AAC15776 AAI38754 AAI38755 BAB27774 BAB31171 BAC27281 EDL39298
RNA Seq Atlas 53330

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca