Homo sapiens Gene: CENPL
Summary
InnateDB Gene IDBG-104888.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol CENPL
Gene Name centromere protein L
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000120334
Encoded Proteins
centromere protein L
centromere protein L
centromere protein L
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary CENPL is a subunit of a CENPH (MIM 605607)-CENPI (MIM 300065)-associated centromeric complex that targets CENPA (MIM 117139) to centromeres and is required for proper kinetochore function and mitotic progression (Okada et al., 2006) [PubMed 16622420].[supplied by OMIM, Mar 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 1:173799550-173824720
Strand Reverse strand
Band q25.1
Transcripts
ENST00000356198 ENSP00000348527
ENST00000345664 ENSP00000323543
ENST00000367710 ENSP00000356683
ENST00000496683
ENST00000460816
ENST00000484920
ENST00000479159
ENST00000493233
ENST00000495275
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 6 experimentally validated interaction(s) in this database.
Experimentally validated
Total 6 [view]
Protein-Protein 6 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
Biological Process
GO:0000278 mitotic cell cycle
Cellular Component
GO:0000775 chromosome, centromeric region
GO:0005634 nucleus
GO:0005829 cytosol
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
Not yet available
Pathways
NETPATH
REACTOME
Resolution of Sister Chromatid Cohesion pathway
Mitotic Prometaphase pathway
Separation of Sister Chromatids pathway
Cell Cycle pathway
M Phase pathway
Mitotic Anaphase pathway
Cell Cycle, Mitotic pathway
Mitotic Metaphase and Anaphase pathway
KEGG
INOH
PID NCI
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Hs.720473
RefSeq NM_001127181 NM_001171182 NM_033319
HUGO
OMIM
CCDS CCDS30938 CCDS44277
HPRD 15909
IMGT
EMBL
GenPept
RNA Seq Atlas