Version 5.4
Homo sapiens Gene: NAV1
Summary
InnateDB Gene IDBG-105776.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol NAV1
Gene Name neuron navigator 1
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000134369
Encoded Proteins
IDBP-105778
neuron navigator 1
IDBP-105788
neuron navigator 1
IDBP-105790
neuron navigator 1
IDBP-389884
neuron navigator 1
IDBP-389885
neuron navigator 1
IDBP-485541
neuron navigator 1
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene belongs to the neuron navigator family and is expressed predominantly in the nervous system. The encoded protein contains coiled-coil domains and a conserved AAA domain characteristic for ATPases associated with a variety of cellular activities. This gene is similar to unc-53, a Caenorhabditis elegans gene involved in axon guidance. The exact function of this gene is not known, but it is thought to play a role in in neuronal development and regeneration. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Nov 2009]
Gene Information
Type Protein coding
Genomic Location Chromosome 1:201622885-201826969
Strand Forward strand
Band q32.1
Transcripts
ENST00000367302 ENSP00000356271
ENST00000367296 ENSP00000356265
ENST00000367295 ENSP00000356264
ENST00000430015 ENSP00000405437
ENST00000438083 ENSP00000389123
ENST00000491403
ENST00000490213
ENST00000469130
ENST00000477118 ENSP00000426436
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 10 experimentally validated interaction(s) in this database.
They are also associated with 2 interaction(s) predicted by orthology.
Experimentally validated
Total 10 [view]
Protein-Protein 10 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 2 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0000166 nucleotide binding
GO:0017111 nucleoside-triphosphatase activity
Biological Process
GO:0001578 microtubule bundle formation
GO:0001764 neuron migration
GO:0008152 metabolic process
Cellular Component
GO:0005737 cytoplasm
GO:0005874 microtubule
GO:0015630 microtubule cytoskeleton
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000009418
View Gene Order
ENSBTAG00000021919
Not yet available
Pathways
NETPATH
NetPath_24
TSLP pathway
REACTOME
KEGG
INOH
PID NCI
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Hs.585374 Hs.601910 Hs.626956 Hs.644932 Hs.700084
RefSeq NM_001167738 NM_020443 XM_005245572 XM_006711607 XM_006711608 XM_006711609 XM_006711610 XM_006711611
HUGO
OMIM
CCDS CCDS1414 CCDS53456
HPRD 10113
IMGT
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca