Homo sapiens Gene: BST1
Summary
InnateDB Gene IDBG-10614.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol BST1
Gene Name bone marrow stromal cell antigen 1
Synonyms CD157
Species Homo sapiens
Ensembl Gene ENSG00000109743
Encoded Proteins
bone marrow stromal cell antigen 1
bone marrow stromal cell antigen 1
bone marrow stromal cell antigen 1
bone marrow stromal cell antigen 1
bone marrow stromal cell antigen 1
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary Bone marrow stromal cell antigen-1 is a stromal cell line-derived glycosylphosphatidylinositol-anchored molecule that facilitates pre-B-cell growth. The deduced amino acid sequence exhibits 33% similarity with CD38. BST1 expression is enhanced in bone marrow stromal cell lines derived from patients with rheumatoid arthritis. The polyclonal B-cell abnormalities in rheumatoid arthritis may be, at least in part, attributed to BST1 overexpression in the stromal cell population. [provided by RefSeq, Jul 2008]
Bone marrow stromal cell antigen-1 is a stromal cell line-derived glycosylphosphatidylinositol-anchored molecule that facilitates pre-B-cell growth. The deduced amino acid sequence exhibits 33%% similarity with CD38. BST1 expression is enhanced in bone marrow stromal cell lines derived from patients with rheumatoid arthritis. The polyclonal B-cell abnormalities in rheumatoid arthritis may be, at least in part, attributed to BST1 overexpression in the stromal cell population. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 4:15702950-15738313
Strand Forward strand
Band p15.32
Transcripts
ENST00000265016 ENSP00000265016
ENST00000382346 ENSP00000371783
ENST00000505785 ENSP00000423357
ENST00000514445 ENSP00000420925
ENST00000514989 ENSP00000424761
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 4 experimentally validated interaction(s) in this database.
Experimentally validated
Total 4 [view]
Protein-Protein 3 [view]
Protein-DNA 1 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0003953 NAD+ nucleosidase activity
GO:0016740 transferase activity
GO:0050135 NAD(P)+ nucleosidase activity
Biological Process
GO:0006959 humoral immune response
GO:0007275 multicellular organismal development
GO:0008152 metabolic process
Cellular Component
GO:0005886 plasma membrane
GO:0019898 extrinsic component of membrane
GO:0031225 anchored component of membrane
GO:0070062 extracellular vesicular exosome
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
Not yet available
Pathways
NETPATH
REACTOME
KEGG
Nicotinate and nicotinamide metabolism pathway
Pancreatic secretion pathway
Salivary secretion pathway
INOH
Nicotinate Nicotinamide metabolism pathway
PID NCI
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene 683
UniGene Hs.720344
RefSeq NM_004334 XM_005248184
HUGO HGNC:1118
OMIM 600387
CCDS CCDS3416
HPRD 02665
IMGT
EMBL
GenPept
RNA Seq Atlas 683