Homo sapiens Gene: BST1 | |||||||||||||||||||
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Summary | |||||||||||||||||||
InnateDB Gene | IDBG-10614.6 | ||||||||||||||||||
Last Modified | 2014-10-13 [Report errors or provide feedback] | ||||||||||||||||||
Gene Symbol | BST1 | ||||||||||||||||||
Gene Name | bone marrow stromal cell antigen 1 | ||||||||||||||||||
Synonyms | CD157 | ||||||||||||||||||
Species | Homo sapiens | ||||||||||||||||||
Ensembl Gene | ENSG00000109743 | ||||||||||||||||||
Encoded Proteins |
bone marrow stromal cell antigen 1
bone marrow stromal cell antigen 1
bone marrow stromal cell antigen 1
bone marrow stromal cell antigen 1
bone marrow stromal cell antigen 1
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Protein Structure | |||||||||||||||||||
Useful resources | Stemformatics EHFPI ImmGen | ||||||||||||||||||
Entrez Gene | |||||||||||||||||||
Summary |
Bone marrow stromal cell antigen-1 is a stromal cell line-derived glycosylphosphatidylinositol-anchored molecule that facilitates pre-B-cell growth. The deduced amino acid sequence exhibits 33% similarity with CD38. BST1 expression is enhanced in bone marrow stromal cell lines derived from patients with rheumatoid arthritis. The polyclonal B-cell abnormalities in rheumatoid arthritis may be, at least in part, attributed to BST1 overexpression in the stromal cell population. [provided by RefSeq, Jul 2008] Bone marrow stromal cell antigen-1 is a stromal cell line-derived glycosylphosphatidylinositol-anchored molecule that facilitates pre-B-cell growth. The deduced amino acid sequence exhibits 33%% similarity with CD38. BST1 expression is enhanced in bone marrow stromal cell lines derived from patients with rheumatoid arthritis. The polyclonal B-cell abnormalities in rheumatoid arthritis may be, at least in part, attributed to BST1 overexpression in the stromal cell population. [provided by RefSeq, Jul 2008] |
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Gene Information | |||||||||||||||||||
Type | Protein coding | ||||||||||||||||||
Genomic Location | Chromosome 4:15702950-15738313 | ||||||||||||||||||
Strand | Forward strand | ||||||||||||||||||
Band | p15.32 | ||||||||||||||||||
Transcripts |
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Interactions | |||||||||||||||||||
Number of Interactions |
This gene and/or its encoded proteins are associated with 4 experimentally validated interaction(s) in this database.
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Gene Ontology | |||||||||||||||||||
Molecular Function |
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Biological Process |
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Cellular Component |
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Orthologs | |||||||||||||||||||
Species
Mus musculus
Bos taurus
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Gene ID
Gene Order
Not yet available
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Pathways | |||||||||||||||||||
NETPATH | |||||||||||||||||||
REACTOME | |||||||||||||||||||
KEGG |
Nicotinate and nicotinamide metabolism pathway
Pancreatic secretion pathway
Salivary secretion pathway
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INOH |
Nicotinate Nicotinamide metabolism pathway
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PID NCI | |||||||||||||||||||
Cross-References | |||||||||||||||||||
SwissProt | |||||||||||||||||||
TrEMBL | |||||||||||||||||||
UniProt Splice Variant | |||||||||||||||||||
Entrez Gene | 683 | ||||||||||||||||||
UniGene | Hs.720344 | ||||||||||||||||||
RefSeq | NM_004334 XM_005248184 | ||||||||||||||||||
HUGO | HGNC:1118 | ||||||||||||||||||
OMIM | 600387 | ||||||||||||||||||
CCDS | CCDS3416 | ||||||||||||||||||
HPRD | 02665 | ||||||||||||||||||
IMGT | |||||||||||||||||||
EMBL | |||||||||||||||||||
GenPept | |||||||||||||||||||
RNA Seq Atlas | 683 | ||||||||||||||||||