Version 5.4
Mus musculus Gene: Pum2
Summary
InnateDB Gene IDBG-128407.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Pum2
Gene Name pumilio 2 (Drosophila)
Synonyms 5730503J23Rik; mKIAA0235; Pumm2
Species Mus musculus
Ensembl Gene ENSMUSG00000020594
Encoded Proteins
IDBP-128409
pumilio 2 (Drosophila)
IDBP-258792
pumilio 2 (Drosophila)
IDBP-258794
pumilio 2 (Drosophila)
IDBP-622898
pumilio 2 (Drosophila)
IDBP-622902
pumilio 2 (Drosophila)
IDBP-622906
pumilio 2 (Drosophila)
IDBP-622908
pumilio 2 (Drosophila)
IDBP-622909
pumilio 2 (Drosophila)
IDBP-622911
pumilio 2 (Drosophila)
IDBP-622913
pumilio 2 (Drosophila)
IDBP-622914
pumilio 2 (Drosophila)
IDBP-622915
pumilio 2 (Drosophila)
IDBP-622917
pumilio 2 (Drosophila)
IDBP-710106
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000055917:
This gene encodes a protein that belongs to a family of RNA-binding proteins. The encoded protein functions as a translational repressor during embryonic development and cell differentiation. This protein is also thought to be a positive regulator of cell proliferation in adipose-derived stem cells. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Sep 2013]
Gene Information
Type Protein coding
Genomic Location Chromosome 12:8674134-8752581
Strand Forward strand
Band A1.1
Transcripts
ENSMUST00000020915 ENSMUSP00000020915
ENSMUST00000111123 ENSMUSP00000106752
ENSMUST00000111122 ENSMUSP00000106751
ENSMUST00000169177
ENSMUST00000165293 ENSMUSP00000132170
ENSMUST00000163569 ENSMUSP00000131074
ENSMUST00000169089 ENSMUSP00000132122
ENSMUST00000169750 ENSMUSP00000126876
ENSMUST00000163730 ENSMUSP00000131914
ENSMUST00000166965 ENSMUSP00000130320
ENSMUST00000170037 ENSMUSP00000127786
ENSMUST00000171418 ENSMUSP00000126616
ENSMUST00000164818 ENSMUSP00000129243
ENSMUST00000171608
ENSMUST00000168361 ENSMUSP00000128292
ENSMUST00000178015 ENSMUSP00000137020
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 4 experimentally validated interaction(s) in this database.
They are also associated with 8 interaction(s) predicted by orthology.
Experimentally validated
Total 4 [view]
Protein-Protein 4 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 8 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003723 RNA binding
GO:0005488 binding
GO:0005515 protein binding
GO:0044822 poly(A) RNA binding
Biological Process
GO:0006417 regulation of translation
GO:0034063 stress granule assembly
Cellular Component
GO:0005737 cytoplasm
GO:0010494 cytoplasmic stress granule
GO:0031965 nuclear membrane
GO:0048471 perinuclear region of cytoplasm
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000055917
View Gene Order
ENSBTAG00000011155
Not yet available
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Mm.341243 Mm.405471 Mm.407110 Mm.419047
RefSeq NM_001160219 NM_001160220 NM_001160221 NM_001160222 NM_030723 XM_006515277 XM_006515278 XM_006515279 XM_006515280 XM_006515281 XM_006515282 XM_006515283 XM_006515284 XM_006515285 XM_006515286
OMIM
CCDS CCDS25802 CCDS49025 CCDS49026
HPRD
IMGT
MGI ID
MGI Symbol
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca