Homo sapiens Gene: THSD7A
Summary
InnateDB Gene IDBG-8643.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol THSD7A
Gene Name thrombospondin, type I, domain containing 7A
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000005108
Encoded Proteins
thrombospondin, type I, domain containing 7A
thrombospondin, type I, domain containing 7A
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary The protein encoded by this gene is found almost exclusively in endothelial cells from placenta and umbilical cord. The encoded protein appears to interact with alpha(V)beta(3) integrin and paxillin to inhibit endothelial cell migration and tube formation. This protein may be involved in cytoskeletal organization. Variations in this gene may be associated with low bone mineral density in osteoporosis. [provided by RefSeq, Aug 2010]
Gene Information
Type Protein coding
Genomic Location Chromosome 7:11370357-11832198
Strand Reverse strand
Band p21.3
Transcripts
ENST00000408005
ENST00000423059 ENSP00000406482
ENST00000497575
ENST00000480061
ENST00000617773 ENSP00000481440
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 4 experimentally validated interaction(s) in this database.
Experimentally validated
Total 4 [view]
Protein-Protein 4 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
Biological Process
GO:0001525 angiogenesis
GO:0030154 cell differentiation
Cellular Component
GO:0005886 plasma membrane
GO:0016021 integral component of membrane
GO:0070062 extracellular vesicular exosome
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
Not yet available
Pathways
NETPATH
REACTOME
Post-translational protein modification pathway
O-linked glycosylation pathway
Metabolism of proteins pathway
O-glycosylation of TSR domain-containing proteins pathway
KEGG
INOH
PID NCI
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Hs.120855
RefSeq NM_015204 XM_006715661
HUGO
OMIM
CCDS CCDS47543
HPRD
IMGT
EMBL
GenPept
RNA Seq Atlas