Version 5.4
Mus musculus Gene: Akap4
Summary
InnateDB Gene IDBG-128910.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Akap4
Gene Name A kinase (PRKA) anchor protein 4
Synonyms AKAP-4; AKAP82; Fsc1; mAKAP82; p82; PRKA4
Species Mus musculus
Ensembl Gene ENSMUSG00000050089
Encoded Proteins
IDBP-128912
A kinase (PRKA) anchor protein 4
IDBP-248953
A kinase (PRKA) anchor protein 4
IDBP-248955
A kinase (PRKA) anchor protein 4
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000147081:
The A-kinase anchor proteins (AKAPs) are a group of structurally diverse proteins, which have the common function of binding to the regulatory subunit of protein kinase A (PKA) and confining the holoenzyme to discrete locations within the cell. This gene encodes a member of the AKAP family. The encoded protein is localized to the sperm flagellum and may be involved in the regulation of sperm motility. Alternative splicing of this gene results in two transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome X:7067519-7078609
Strand Forward strand
Band A1.1
Transcripts
ENSMUST00000057101 ENSMUSP00000050962
ENSMUST00000115751 ENSMUSP00000111417
ENSMUST00000115750 ENSMUSP00000111416
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
They are also associated with 6 interaction(s) predicted by orthology.
Experimentally validated
Total 1 [view]
Protein-Protein 1 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 6 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
GO:0051018 protein kinase A binding
Biological Process
GO:0007178 transmembrane receptor protein serine/threonine kinase signaling pathway
GO:0008104 protein localization
GO:0030030 cell projection organization
GO:0030317 sperm motility
Cellular Component
GO:0005634 nucleus
GO:0005929 cilium
GO:0030018 Z disc
GO:0031514 motile cilium
GO:0035686 sperm fibrous sheath
GO:0048471 perinuclear region of cytoplasm
GO:0097228 sperm principal piece
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000147081
View Gene Order
ENSBTAG00000016399
Not yet available
Cross-References
SwissProt Q60662
TrEMBL A1L3T6
UniProt Splice Variant
Entrez Gene 11643
UniGene Mm.1498
RefSeq NM_009651 XM_006544490 NM_001042542
OMIM
CCDS CCDS40838 CCDS40839
HPRD
IMGT
MGI ID MGI:102794
MGI Symbol Akap4
EMBL AF448784 AF448785 AF448786 AL808124 BC130271 U07423 U10341
GenPept AAA53216 AAA75597 AAI30272 AAM18539 AAM18540 CAM15283
RNA Seq Atlas 102642117 11643

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca