Version 5.4
Mus musculus Gene: Capza2
Summary
InnateDB Gene IDBG-129053.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Capza2
Gene Name capping protein (actin filament) muscle Z-line, alpha 2
Synonyms 1110053K06Rik; AW208808; Cappa2
Species Mus musculus
Ensembl Gene ENSMUSG00000015733
Encoded Proteins
IDBP-129055
capping protein (actin filament) muscle Z-line, alpha 2
IDBP-535203
capping protein (actin filament) muscle Z-line, alpha 2
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000198898:
The protein encoded by this gene is a member of the F-actin capping protein alpha subunit family. It is the alpha subunit of the barbed-end actin binding protein Cap Z. By capping the barbed end of actin filaments, Cap Z regulates the growth of the actin filaments at the barbed end. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 6:17636234-17666972
Strand Forward strand
Band A2
Transcripts
ENSMUST00000015877 ENSMUSP00000015877
ENSMUST00000148694
ENSMUST00000156701
ENSMUST00000136771
ENSMUST00000130606 ENSMUSP00000123398
ENSMUST00000152005
ENSMUST00000142592
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 16 experimentally validated interaction(s) in this database.
They are also associated with 10 interaction(s) predicted by orthology.
Experimentally validated
Total 16 [view]
Protein-Protein 15 [view]
Protein-DNA 1 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 10 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003779 actin binding
GO:0005515 protein binding
Biological Process
GO:0008150 biological_process
GO:0030036 actin cytoskeleton organization
GO:0051693 actin filament capping
Cellular Component
GO:0008290 F-actin capping protein complex
GO:0016020 membrane
GO:0030863 cortical cytoskeleton
GO:0070062 extracellular vesicular exosome
GO:0071203 WASH complex
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000198898
View Gene Order
ENSBTAG00000004072
Not yet available
Pathways
NETPATH
REACTOME
REACT_239142
Innate Immune System pathway
REACT_224553
Hemostasis pathway
REACT_230745
Immune System pathway
REACT_198647
Advanced glycosylation endproduct receptor signaling pathway
REACT_198649
Factors involved in megakaryocyte development and platelet production pathway
KEGG
INOH
PID NCI
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
REACT_25195
Advanced glycosylation endproduct receptor signaling pathway
REACT_24970
Factors involved in megakaryocyte development and platelet production pathway
REACT_6802
Innate Immune System pathway
REACT_6900
Immune System pathway
REACT_604
Hemostasis pathway
REACT_215067
Factors involved in megakaryocyte development and platelet production pathway
REACT_212196
Hemostasis pathway
REACT_213138
Immune System pathway
REACT_204725
Advanced glycosylation endproduct receptor signaling pathway
REACT_216714
Innate Immune System pathway
KEGG
INOH
PID NCI
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Mm.392504 Mm.471667
RefSeq NM_007604
OMIM
CCDS CCDS19926
HPRD
IMGT
MGI ID
MGI Symbol
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca