InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Gene: Taf4b

Summary

InnateDB Gene

IDBG-129447.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Taf4b

Gene Name

TAF4B RNA polymerase II, TATA box binding protein (TBP)-associated factor

Synonyms

105kDa; 2610524B04Rik; 4932409F03Rik; AW987595; Taf2c2; TAFII105

Species

Mus musculus

Ensembl Gene

ENSMUSG00000054321

Encoded Proteins

IDBP-621420

TAF4B RNA polymerase II, TATA box binding protein (TBP)-associated factor

Protein Structure

Useful resources

Stemformatics EHFPI ImmGen

Entrez Gene

Summary

This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000141384:
TATA binding protein (TBP) and TBP-associated factors (TAFs) participate in the formation of the TFIID protein complex, which is involved in initiation of transcription of genes by RNA polymerase II. This gene encodes a cell type-specific TAF that may be responsible for mediating transcription by a subset of activators in B cells. [provided by RefSeq, Sep 2011]
TATA binding protein (TBP) and TBP-associated factors (TAFs) participate in the formation of the TFIID protein complex, which is involved in initiation of transcription of genes by RNA polymerase II. This gene encodes a cell type-specific TAF that may be responsible for mediating transcription by a subset of activators in B cells. Three transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq, Jun 2014]

Gene Information

Type

Protein coding

Genomic Location

Chromosome 18:14783245-14900359

Strand

Forward strand

Band

Transcripts

ENSMUST00000169862

ENSMUSP00000126909

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 6 interaction(s) predicted by orthology.

Predicted by orthology
Total	6 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0003677	DNA binding
GO:0003700	sequence-specific DNA binding transcription factor activity
GO:0046982	protein heterodimerization activity
GO:0051059	NF-kappaB binding

Biological Process

GO:0006352	DNA-templated transcription, initiation
GO:0006355	regulation of transcription, DNA-templated
GO:0006357	regulation of transcription from RNA polymerase II promoter
GO:0006366	transcription from RNA polymerase II promoter