InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Gene: Slc35a2

Summary

InnateDB Gene

IDBG-129677.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Slc35a2

Gene Name

solute carrier family 35 (UDP-galactose transporter), member A2

Synonyms

AI327289; Had-1; Had1; Sfc8; Ugalt; UGT

Species

Mus musculus

Ensembl Gene

ENSMUSG00000031156

Encoded Proteins

IDBP-129681

solute carrier family 35 (UDP-galactose transporter), member A2

IDBP-249146

solute carrier family 35 (UDP-galactose transporter), member A2

IDBP-249148

solute carrier family 35 (UDP-galactose transporter), member A2

IDBP-542092

solute carrier family 35 (UDP-galactose transporter), member A2

IDBP-537396

solute carrier family 35 (UDP-galactose transporter), member A2

Protein Structure

Useful resources

Stemformatics EHFPI ImmGen

Entrez Gene

Summary

This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000102100:
This gene encodes a member of the nucleotide-sugar transporter family. The encoded protein is a multi-pass membrane protein. It transports UDP-galactose from the cytosol into Golgi vesicles, where it serves as a glycosyl donor for the generation of glycans. Mutations in this gene cause congenital disorder of glycosylation type IIm (CDG2M). Multiple alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq, Oct 2014]

Gene Information

Type

Protein coding

Genomic Location

Chromosome X:7884041-7894492

Strand

Forward strand

Band

A1.1

Transcripts

ENSMUST00000096514	ENSMUSP00000094259
ENSMUST00000115663	ENSMUSP00000111327
ENSMUST00000115660	ENSMUSP00000111324
ENSMUST00000123277	ENSMUSP00000116270
ENSMUST00000153620	ENSMUSP00000120681
ENSMUST00000155967

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 3 interaction(s) predicted by orthology.

Predicted by orthology
Total	3 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0005338	nucleotide-sugar transmembrane transporter activity
GO:0005351	sugar:proton symporter activity
GO:0005459	UDP-galactose transmembrane transporter activity
GO:0005515	protein binding

Biological Process

GO:0006810	transport
GO:0008643	carbohydrate transport
GO:0015780	nucleotide-sugar transport
GO:0015992	proton transport
GO:0055085	transmembrane transport
GO:0072334	UDP-galactose transmembrane transport

Cellular Component

GO:0000139	Golgi membrane
GO:0005634	nucleus
GO:0005794	Golgi apparatus
GO:0016020	membrane
GO:0016021	integral component of membrane

Orthologs

Species

Homo sapiens

Bos taurus

Gene ID

Gene Order

ENSG00000102100

View Gene Order

ENSBTAG00000002768

Not yet available

Pathways

NETPATH

REACTOME

REACT_247550

SLC-mediated transmembrane transport pathway

REACT_232951

Transport of vitamins, nucleosides, and related molecules pathway

REACT_253400

Transmembrane transport of small molecules pathway

REACT_203051

Transport of nucleotide sugars pathway

KEGG

INOH

PID NCI

Pathway Predictions based on Human Orthology Data

NETPATH

REACTOME

REACT_22151

Transport of nucleotide sugars pathway

REACT_22285

Transport of vitamins, nucleosides, and related molecules pathway

REACT_15518

Transmembrane transport of small molecules pathway

REACT_19118

SLC-mediated transmembrane transport pathway

KEGG

INOH

PID NCI

Cross-References

SwissProt

TrEMBL

A2AER3 Q3U1T6

UniProt Splice Variant

Entrez Gene

22232

UniGene

Mm.214976 Mm.416415

RefSeq

NM_001083937 NM_078484

OMIM

CCDS

CCDS52986 CCDS52987

HPRD

IMGT

MGI ID

MGI:1345297

MGI Symbol

Slc35a2

EMBL

AK155732 AL671978

GenPept

BAE33407

RNA Seq Atlas

22232