Version 5.4
Bos taurus Gene: SLC35A2
Summary
InnateDB Gene IDBG-636941.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol SLC35A2
Gene Name UDP-galactose translocator
Synonyms UGT
Species Bos taurus
Ensembl Gene ENSBTAG00000002768
Encoded Proteins
IDBP-688918
UDP-galactose translocator
IDBP-688923
UDP-galactose translocator
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000102100:
This gene encodes a member of the nucleotide-sugar transporter family. The encoded protein is a multi-pass membrane protein. It transports UDP-galactose from the cytosol into Golgi vesicles, where it serves as a glycosyl donor for the generation of glycans. Mutations in this gene cause congenital disorder of glycosylation type IIm (CDG2M). Multiple alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq, Oct 2014]
Gene Information
Type Protein coding
Genomic Location Chromosome X:92098162-92105518
Strand Reverse strand
Band
Transcripts
ENSBTAT00000003591 ENSBTAP00000003591
ENSBTAT00000045026 ENSBTAP00000042455
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 3 interaction(s) predicted by orthology.
Predicted by orthology
Total 3 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005338 nucleotide-sugar transmembrane transporter activity
GO:0005351 sugar:proton symporter activity
GO:0005459 UDP-galactose transmembrane transporter activity
GO:0005515 protein binding
Biological Process
GO:0006810 transport
GO:0008643 carbohydrate transport
GO:0015780 nucleotide-sugar transport
GO:0015992 proton transport
GO:0055085 transmembrane transport
GO:0072334 UDP-galactose transmembrane transport
GO:1901679 nucleotide transmembrane transport
Cellular Component
GO:0000139 Golgi membrane
GO:0005634 nucleus
GO:0005794 Golgi apparatus
GO:0016020 membrane
GO:0016021 integral component of membrane
Orthologs
Species
Homo sapiens
Mus musculus
Gene ID
Gene Order
ENSG00000102100
View Gene Order
ENSMUSG00000031156
View Gene Order
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
REACT_22151
Transport of nucleotide sugars pathway
REACT_22285
Transport of vitamins, nucleosides, and related molecules pathway
REACT_15518
Transmembrane transport of small molecules pathway
REACT_19118
SLC-mediated transmembrane transport pathway
REACT_247550
SLC-mediated transmembrane transport pathway
REACT_232951
Transport of vitamins, nucleosides, and related molecules pathway
REACT_253400
Transmembrane transport of small molecules pathway
REACT_203051
Transport of nucleotide sugars pathway
KEGG
INOH
PID NCI
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Bt.16019
RefSeq NM_176640
HUGO
OMIM
CCDS
HPRD
IMGT
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca