Version 5.4
Mus musculus Gene: Catsper1
Summary
InnateDB Gene IDBG-131236.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Catsper1
Gene Name cation channel, sperm associated 1
Synonyms
Species Mus musculus
Ensembl Gene ENSMUSG00000038498
Encoded Proteins
IDBP-131238
cation channel, sperm associated 1
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000175294:
Calcium ions play a primary role in the regulation of sperm motility. This gene belongs to a family of putative cation channels that are specific to spermatozoa and localize to the flagellum. The protein family features a single repeat with six membrane-spanning segments and a predicted calcium-selective pore region. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 19:5335741-5344153
Strand Forward strand
Band A
Transcripts
ENSMUST00000043380 ENSMUSP00000045430
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 8 experimentally validated interaction(s) in this database.
They are also associated with 8 interaction(s) predicted by orthology.
Experimentally validated
Total 8 [view]
Protein-Protein 6 [view]
Protein-DNA 2 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 8 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005216 ion channel activity
GO:0005227 calcium activated cation channel activity
GO:0005245 voltage-gated calcium channel activity
GO:0005515 protein binding
Biological Process
GO:0006811 ion transport
GO:0006816 calcium ion transport
GO:0007275 multicellular organismal development
GO:0007283 spermatogenesis
GO:0007342 fusion of sperm to egg plasma membrane
GO:0030154 cell differentiation
GO:0030317 sperm motility
GO:0034765 regulation of ion transmembrane transport
GO:0051924 regulation of calcium ion transport
GO:0055085 transmembrane transport
GO:0060296 regulation of cilium beat frequency involved in ciliary motility
GO:0070509 calcium ion import
GO:0086010 membrane depolarization during action potential
Cellular Component
GO:0005886 plasma membrane
GO:0005929 cilium
GO:0016020 membrane
GO:0036128 CatSper complex
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000175294
View Gene Order
ENSBTAG00000014720
Not yet available
Pathways
NETPATH
REACTOME
REACT_196630
Sperm Motility And Taxes pathway
REACT_199082
Fertilization pathway
REACT_199085
Reproduction pathway
KEGG
INOH
PID NCI
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
REACT_163914
Fertilization pathway
REACT_163875
Sperm Motility And Taxes pathway
REACT_163848
Reproduction pathway
KEGG
INOH
PID NCI
Cross-References
SwissProt Q91ZR5
TrEMBL
UniProt Splice Variant
Entrez Gene 225865
UniGene Mm.87321
RefSeq NM_139301
OMIM
CCDS CCDS29456
HPRD
IMGT
MGI ID MGI:2179947
MGI Symbol Catsper1
EMBL AF407332 DQ021482 DQ021483 DQ021484 DQ021485 DQ021486 DQ021488 DQ021489 DQ021490 DQ021491 DQ021492
GenPept AAL14104 AAY63820 AAY63821 AAY63822 AAY63823 AAY63824 AAY63826 AAY63827 AAY63828 AAY63829 AAY63830
RNA Seq Atlas 225865

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca