Version 5.4
Mus musculus Gene: Arid4b
Summary
InnateDB Gene IDBG-131316.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Arid4b
Gene Name AT rich interactive domain 4B (RBP1-like)
Synonyms BCAA; BRCAA1; RBBP1L1; Rbp1l1; SAP180
Species Mus musculus
Ensembl Gene ENSMUSG00000039219
Encoded Proteins
IDBP-131318
AT rich interactive domain 4B (RBP1-like)
IDBP-260057
AT rich interactive domain 4B (RBP1-like)
IDBP-260059
AT rich interactive domain 4B (RBP1-like)
IDBP-260061
AT rich interactive domain 4B (RBP1-like)
IDBP-539358
AT rich interactive domain 4B (RBP1-like)
IDBP-539532
AT rich interactive domain 4B (RBP1-like)
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000054267:
This gene encodes a protein with sequence similarity to retinoblastoma-binding protein-1. The encoded protein is a subunit of the histone deacetylase-dependant SIN3A transcriptional corepressor complex, which functions in diverse cellular processes including proliferation, differentiation, apoptosis, oncogenesis, and cell fate determination. The gene product is recognized by IgG antibody isolated from a breast cancer patient and appears to be a molecular marker associated with a broad range of human malignancies. Alternate transcriptional splice variants encoding different isoforms have been characterized. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 13:14063232-14199603
Strand Forward strand
Band A1
Transcripts
ENSMUST00000039538 ENSMUSP00000043889
ENSMUST00000110536 ENSMUSP00000106165
ENSMUST00000110534 ENSMUSP00000106163
ENSMUST00000110533 ENSMUSP00000106162
ENSMUST00000155553
ENSMUST00000129488 ENSMUSP00000118687
ENSMUST00000151182
ENSMUST00000149579 ENSMUSP00000119147
ENSMUST00000148941
ENSMUST00000151151
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 4 experimentally validated interaction(s) in this database.
They are also associated with 13 interaction(s) predicted by orthology.
Experimentally validated
Total 4 [view]
Protein-Protein 4 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 13 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003677 DNA binding
GO:0005515 protein binding
Biological Process
GO:0006349 regulation of gene expression by genetic imprinting
GO:0006351 transcription, DNA-templated
GO:0006355 regulation of transcription, DNA-templated
GO:0034773 histone H4-K20 trimethylation
GO:0036124 histone H3-K9 trimethylation
Cellular Component
GO:0005575 cellular_component
GO:0005622 intracellular
GO:0005634 nucleus
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000054267
View Gene Order
ENSBTAG00000000222
Not yet available
Pathways
NETPATH
REACTOME
REACT_218274
Chromatin organization pathway
REACT_202766
Chromatin modifying enzymes pathway
REACT_257106
HDACs deacetylate histones pathway
KEGG
INOH
PID NCI
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
REACT_200857
Epigenetic regulation of gene expression pathway
REACT_200856
NoRC negatively regulates rRNA expression pathway
REACT_228222
HDACs deacetylate histones pathway
REACT_172623
Chromatin organization pathway
REACT_172633
Chromatin modifying enzymes pathway
REACT_71
Gene Expression pathway
REACT_200834
Negative epigenetic regulation of rRNA expression pathway
KEGG
INOH
PID NCI
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene 94246
UniGene Mm.436478 Mm.439784 Mm.450893
RefSeq NM_194262 NM_198122 XM_006516806 XM_006516807
OMIM
CCDS CCDS36599 CCDS36600
HPRD
IMGT
MGI ID MGI:2137512
MGI Symbol Arid4b
EMBL
GenPept
RNA Seq Atlas 94246

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca