Bos taurus Gene: ARID4B
Summary
InnateDB Gene IDBG-628482.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol ARID4B
Gene Name AT-rich interactive domain-containing protein 4B
Synonyms
Species Bos taurus
Ensembl Gene ENSBTAG00000000222
Encoded Proteins
AT rich interactive domain 4B (RBP1-like)
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000054267:
This gene encodes a protein with sequence similarity to retinoblastoma-binding protein-1. The encoded protein is a subunit of the histone deacetylase-dependant SIN3A transcriptional corepressor complex, which functions in diverse cellular processes including proliferation, differentiation, apoptosis, oncogenesis, and cell fate determination. The gene product is recognized by IgG antibody isolated from a breast cancer patient and appears to be a molecular marker associated with a broad range of human malignancies. Alternate transcriptional splice variants encoding different isoforms have been characterized. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 28:7972951-8109684
Strand Reverse strand
Band
Transcripts
ENSBTAT00000061477 ENSBTAP00000053446
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 14 interaction(s) predicted by orthology.
Predicted by orthology
Total 14 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003677 DNA binding
GO:0005515 protein binding
Biological Process
GO:0006349 regulation of gene expression by genetic imprinting
GO:0006355 regulation of transcription, DNA-templated
GO:0034773 histone H4-K20 trimethylation
GO:0036124 histone H3-K9 trimethylation
Cellular Component
GO:0005622 intracellular
GO:0005634 nucleus
Orthologs
Species
Homo sapiens
Mus musculus
Gene ID
Gene Order
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
Epigenetic regulation of gene expression pathway
NoRC negatively regulates rRNA expression pathway
HDACs deacetylate histones pathway
Chromatin organization pathway
Chromatin modifying enzymes pathway
Gene Expression pathway
Negative epigenetic regulation of rRNA expression pathway
Chromatin organization pathway
Chromatin modifying enzymes pathway
HDACs deacetylate histones pathway
KEGG
INOH
PID NCI
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Bt.38433
RefSeq NM_001206133 XM_005226222 XM_005226223
HUGO
OMIM
CCDS
HPRD
IMGT
EMBL
GenPept
RNA Seq Atlas