Version 5.4
Mus musculus Gene: Ggh
Summary
InnateDB Gene IDBG-131323.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Ggh
Gene Name gamma-glutamyl hydrolase
Synonyms gamma-GH
Species Mus musculus
Ensembl Gene ENSMUSG00000073987
Encoded Proteins
IDBP-131325
gamma-glutamyl hydrolase
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000137563:
This gene catalyzes the hydrolysis of folylpoly-gamma-glutamates and antifolylpoly-gamma-glutamates by the removal of gamma-linked polyglutamates and glutamate. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 4:20042052-20066750
Strand Forward strand
Band A3
Transcripts
ENSMUST00000098242 ENSMUSP00000095843
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 7 interaction(s) predicted by orthology.
Predicted by orthology
Total 7 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0016787 hydrolase activity
GO:0034722 gamma-glutamyl-peptidase activity
Biological Process
GO:0006508 proteolysis
GO:0006541 glutamine metabolic process
GO:0010043 response to zinc ion
GO:0032868 response to insulin
GO:0042493 response to drug
GO:0045471 response to ethanol
Cellular Component
GO:0005615 extracellular space
GO:0005634 nucleus
GO:0005764 lysosome
GO:0005829 cytosol
GO:0042470 melanosome
GO:0070062 extracellular vesicular exosome
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000137563
View Gene Order
ENSBTAG00000007534
Not yet available
Pathways
NETPATH
REACTOME
KEGG
mmu00790
Folate biosynthesis pathway
INOH
PID NCI
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
KEGG
hsa00790
Folate biosynthesis pathway
INOH
PID NCI
Cross-References
SwissProt Q9Z0L8
TrEMBL
UniProt Splice Variant
Entrez Gene 14590
UniGene Mm.20461 Mm.410080 Mm.445534
RefSeq NM_010281
OMIM
CCDS CCDS51126
HPRD
IMGT
MGI ID MGI:1329035
MGI Symbol Ggh
EMBL AF051102 AF051103 AF090725 AF090726 AF090727 AF090728 AF090729 AF090730 AF090731 AF090732 AL732527 CR931798
GenPept AAC70002 AAC70003 AAD47388 CAM18838 CAO78172
RNA Seq Atlas 14590

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca