Version 5.4
| Mus musculus Gene: Hecw1 | |||||||||
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| Summary | |||||||||
| InnateDB Gene | IDBG-131468.6 | ||||||||
| Last Modified | 2014-10-13 [Report errors or provide feedback] | ||||||||
| Gene Symbol | Hecw1 | ||||||||
| Gene Name | HECT, C2 and WW domain containing E3 ubiquitin protein ligase 1 | ||||||||
| Synonyms | 9330116H24Rik; AV273951; E130207I19Rik; Nedl1 | ||||||||
| Species | Mus musculus | ||||||||
| Ensembl Gene | ENSMUSG00000021301 | ||||||||
| Encoded Proteins |
HECT, C2 and WW domain containing E3 ubiquitin protein ligase 1
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| Protein Structure |
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| Useful resources | Stemformatics EHFPI ImmGen | ||||||||
| Entrez Gene | |||||||||
| Summary |
This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000002746:
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| Gene Information | |||||||||
| Type | Protein coding | ||||||||
| Genomic Location | Chromosome 13:14226438-14523226 | ||||||||
| Strand | Reverse strand | ||||||||
| Band | A1 | ||||||||
| Transcripts |
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| Interactions | |||||||||
| Number of Interactions |
This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 13 interaction(s) predicted by orthology.
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| Gene Ontology | |||||||||
Molecular Function |
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| Biological Process |
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| Cellular Component |
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| Orthologs | |||||||||
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Species
Homo sapiens
Bos taurus
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Gene ID
Gene Order
Not yet available
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| Pathways | |||||||||
| NETPATH | |||||||||
| REACTOME |
Disease pathway
Signaling by Wnt pathway
Signaling by WNT in cancer pathway
degradation of DVL pathway
misspliced LRP5 mutants have enhanced beta-catenin-dependent signaling pathway
RNF mutants show enhanced WNT signaling and proliferation pathway
TCF dependent signaling in response to WNT pathway
Signal Transduction pathway
XAV939 inhibits tankyrase, stabilizing AXIN pathway
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| KEGG | |||||||||
| INOH | |||||||||
| PID NCI | |||||||||
| Pathway Predictions based on Human Orthology Data | |||||||||
| NETPATH | |||||||||
| REACTOME |
misspliced LRP5 mutants have enhanced beta-catenin-dependent signaling pathway
Signaling by WNT in cancer pathway
Signaling by Wnt pathway
degradation of DVL pathway
Signal Transduction pathway
TCF dependent signaling in response to WNT pathway
RNF mutants show enhanced WNT signaling and proliferation pathway
XAV939 inhibits tankyrase, stabilizing AXIN pathway
Disease pathway
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| KEGG | |||||||||
| INOH | |||||||||
| PID NCI | |||||||||
| Cross-References | |||||||||
| SwissProt | Q8K4P8 | ||||||||
| TrEMBL | |||||||||
| UniProt Splice Variant | |||||||||
| Entrez Gene | 94253 | ||||||||
| UniGene | Mm.125298 Mm.422150 | ||||||||
| RefSeq | NM_001081348 XM_006516809 XM_006516810 XM_006516811 XM_006516812 XM_006516814 | ||||||||
| OMIM | |||||||||
| CCDS | CCDS49207 | ||||||||
| HPRD | |||||||||
| IMGT | |||||||||
| MGI ID | MGI:2444115 | ||||||||
| MGI Symbol | Hecw1 | ||||||||
| EMBL | AB083710 AC092710 AC154511 AC154615 AC161249 AK033922 AK047678 AK051569 AK053694 AK172932 CT025604 | ||||||||
| GenPept | BAB97389 BAC28516 BAC33122 BAC34677 BAC35477 BAD32210 | ||||||||
| RNA Seq Atlas | 94253 | ||||||||