Version 5.4
Mus musculus Gene: Lass4
Summary
InnateDB Gene IDBG-131517.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Lass4
Gene Name LAG1 homolog, ceramide synthase 4
Synonyms 2900019C14Rik; Lass4; Trh1
Species Mus musculus
Ensembl Gene ENSMUSG00000008206
Encoded Proteins
IDBP-131519
LAG1 homolog, ceramide synthase 4
IDBP-788325
ceramide synthase 4
IDBP-718096
IDBP-716189
IDBP-716451
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000090661:
Gene Information
Type Protein coding
Genomic Location Chromosome 8:4493026-4531680
Strand Forward strand
Band A1.1
Transcripts
ENSMUST00000008350 ENSMUSP00000008350
ENSMUST00000176267
ENSMUST00000175781 ENSMUSP00000138819
ENSMUST00000177010 ENSMUSP00000135763
ENSMUST00000176837
ENSMUST00000176705
ENSMUST00000176042 ENSMUSP00000135594
ENSMUST00000176932
ENSMUST00000176130 ENSMUSP00000135652
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
Experimentally validated
Total 1 [view]
Protein-Protein 1 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0003677 DNA binding
GO:0003700 sequence-specific DNA binding transcription factor activity
GO:0043565 sequence-specific DNA binding
GO:0050291 sphingosine N-acyltransferase activity
Biological Process
GO:0006355 regulation of transcription, DNA-templated
GO:0030148 sphingolipid biosynthetic process
GO:0046513 ceramide biosynthetic process
Cellular Component
GO:0005634 nucleus
GO:0005783 endoplasmic reticulum
GO:0005789 endoplasmic reticulum membrane
GO:0016021 integral component of membrane
GO:0031965 nuclear membrane
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000090661
View Gene Order
ENSBTAG00000003434
Not yet available
Pathways
NETPATH
REACTOME
REACT_198151
Sphingolipid de novo biosynthesis pathway
REACT_188937
Metabolism pathway
REACT_245163
Sphingolipid metabolism pathway
REACT_232291
Metabolism of lipids and lipoproteins pathway
KEGG
mmu00600
Sphingolipid metabolism pathway
INOH
PID NCI
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
REACT_115810
Sphingolipid de novo biosynthesis pathway
REACT_19323
Sphingolipid metabolism pathway
REACT_22258
Metabolism of lipids and lipoproteins pathway
REACT_111217
Metabolism pathway
REACT_204257
Sphingolipid de novo biosynthesis pathway
REACT_222556
Sphingolipid metabolism pathway
REACT_219933
Metabolism of lipids and lipoproteins pathway
REACT_219139
Metabolism pathway
KEGG
hsa00600
Sphingolipid metabolism pathway
INOH
PID NCI
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Mm.35511 Mm.411101 Mm.483411
RefSeq NM_026058 XM_006508861 XM_006508862
OMIM
CCDS CCDS22086
HPRD
IMGT
MGI ID
MGI Symbol
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca