Version 5.4
Mus musculus Gene: Tnpo3
Summary
InnateDB Gene IDBG-132095.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Tnpo3
Gene Name transportin 3
Synonyms
Species Mus musculus
Ensembl Gene ENSMUSG00000012535
Encoded Proteins
IDBP-132097
transportin 3
IDBP-250040
transportin 3
IDBP-624932
transportin 3
IDBP-624940
transportin 3
IDBP-624946
transportin 3
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000064419:
The protein encoded by this gene is a nuclear import receptor for serine/arginine-rich (SR) proteins such as the splicing factors SFRS1 and SFRS2. The encoded protein has also been shown to be involved in HIV-1 infection, apparently through interaction with the HIV-1 capsid protein. Two transcript variants encoding different isoforms as well as a noncoding transcript have been found for this gene.[provided by RefSeq, Jul 2010]
Gene Information
Type Protein coding
Genomic Location Chromosome 6:29540827-29609887
Strand Reverse strand
Band A3.3
Transcripts
ENSMUST00000012679 ENSMUSP00000012679
ENSMUST00000115251 ENSMUSP00000110906
ENSMUST00000170647 ENSMUSP00000133115
ENSMUST00000170350 ENSMUSP00000131411
ENSMUST00000171865
ENSMUST00000169302
ENSMUST00000167056
ENSMUST00000170634
ENSMUST00000164325
ENSMUST00000166844 ENSMUSP00000131699
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
They are also associated with 17 interaction(s) predicted by orthology.
Experimentally validated
Total 1 [view]
Protein-Protein 1 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 17 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003674 molecular_function
GO:0005488 binding
GO:0005515 protein binding
Biological Process
GO:0035048 splicing factor protein import into nucleus
Cellular Component
GO:0005634 nucleus
GO:0005737 cytoplasm
GO:0043231 intracellular membrane-bounded organelle
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000064419
View Gene Order
ENSBTAG00000004992
Not yet available
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Mm.276381
RefSeq NM_177296 XM_006505119 XM_006505120 XM_006505121
OMIM
CCDS CCDS19963
HPRD
IMGT
MGI ID
MGI Symbol
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca