Version 5.4
Mus musculus Gene: Suv39h2
Summary
InnateDB Gene IDBG-133332.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Suv39h2
Gene Name suppressor of variegation 3-9 homolog 2 (Drosophila)
Synonyms 4930507K23Rik; AA536750; D030054H19Rik; D2Ertd544e; KMT1B
Species Mus musculus
Ensembl Gene ENSMUSG00000026646
Encoded Proteins
IDBP-133334
suppressor of variegation 3-9 homolog 2 (Drosophila)
IDBP-133336
suppressor of variegation 3-9 homolog 2 (Drosophila)
IDBP-133338
suppressor of variegation 3-9 homolog 2 (Drosophila)
IDBP-537673
suppressor of variegation 3-9 homolog 2 (Drosophila)
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000152455:
Gene Information
Type Protein coding
Genomic Location Chromosome 2:3455815-3475031
Strand Reverse strand
Band A1
Transcripts
ENSMUST00000027956 ENSMUSP00000027956
ENSMUST00000060618 ENSMUSP00000054169
ENSMUST00000100458 ENSMUSP00000098026
ENSMUST00000127540 ENSMUSP00000125485
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 4 experimentally validated interaction(s) in this database.
They are also associated with 19 interaction(s) predicted by orthology.
Experimentally validated
Total 4 [view]
Protein-Protein 4 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 19 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0000976 transcription regulatory region sequence-specific DNA binding
GO:0003682 chromatin binding
GO:0005515 protein binding
GO:0008168 methyltransferase activity
GO:0008270 zinc ion binding
GO:0008276 protein methyltransferase activity
GO:0018024 histone-lysine N-methyltransferase activity
GO:0046974 histone methyltransferase activity (H3-K9 specific)
Biological Process
GO:0006333 chromatin assembly or disassembly
GO:0006338 chromatin remodeling
GO:0006351 transcription, DNA-templated
GO:0007140 male meiosis
GO:0030154 cell differentiation
GO:0034968 histone lysine methylation
GO:0036123 histone H3-K9 dimethylation
GO:0036124 histone H3-K9 trimethylation
GO:0042754 negative regulation of circadian rhythm
GO:0045892 negative regulation of transcription, DNA-templated
GO:0051567 histone H3-K9 methylation
Cellular Component
GO:0000775 chromosome, centromeric region
GO:0000785 chromatin
GO:0005634 nucleus
GO:0005720 nuclear heterochromatin
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000152455
View Gene Order
ENSBTAG00000010210
Not yet available
Pathways
NETPATH
REACTOME
KEGG
mmu00310
Lysine degradation pathway
INOH
PID NCI
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
KEGG
hsa00310
Lysine degradation pathway
INOH
PID NCI
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Mm.128273 Mm.486371
RefSeq NM_022724
OMIM
CCDS CCDS15652
HPRD
IMGT
MGI ID
MGI Symbol
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca