Version 5.4
Homo sapiens Gene: SUV39H2
Summary
InnateDB Gene IDBG-56187.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol SUV39H2
Gene Name suppressor of variegation 3-9 homolog 2 (Drosophila)
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000152455
Encoded Proteins
IDBP-56189
suppressor of variegation 3-9 homolog 2 (Drosophila)
IDBP-56191
suppressor of variegation 3-9 homolog 2 (Drosophila)
IDBP-56193
suppressor of variegation 3-9 homolog 2 (Drosophila)
IDBP-56195
suppressor of variegation 3-9 homolog 2 (Drosophila)
IDBP-56197
suppressor of variegation 3-9 homolog 2 (Drosophila)
IDBP-366793
suppressor of variegation 3-9 homolog 2 (Drosophila)
IDBP-366805
suppressor of variegation 3-9 homolog 2 (Drosophila)
IDBP-366810
suppressor of variegation 3-9 homolog 2 (Drosophila)
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary Currently no Entrez Summary Available. You might want to check the Summary Sections of the Orthologs.
Gene Information
Type Protein coding
Genomic Location Chromosome 10:14878820-14904315
Strand Forward strand
Band p13
Transcripts
ENST00000378331 ENSP00000367582
ENST00000378325 ENSP00000367576
ENST00000354919 ENSP00000346997
ENST00000358298 ENSP00000351046
ENST00000313519 ENSP00000319208
ENST00000433779 ENSP00000388968
ENST00000420416 ENSP00000392201
ENST00000412254 ENSP00000388218
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 70 experimentally validated interaction(s) in this database.
They are also associated with 2 interaction(s) predicted by orthology.
Experimentally validated
Total 70 [view]
Protein-Protein 70 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 2 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0000976 transcription regulatory region sequence-specific DNA binding
GO:0003682 chromatin binding
GO:0005515 protein binding
GO:0008168 methyltransferase activity
GO:0008270 zinc ion binding
GO:0008276 protein methyltransferase activity
GO:0018024 histone-lysine N-methyltransferase activity
GO:0046974 histone methyltransferase activity (H3-K9 specific)
Biological Process
GO:0006333 chromatin assembly or disassembly
GO:0006338 chromatin remodeling
GO:0006351 transcription, DNA-templated
GO:0007140 male meiosis
GO:0030154 cell differentiation
GO:0034968 histone lysine methylation
GO:0036123 histone H3-K9 dimethylation
GO:0036124 histone H3-K9 trimethylation
GO:0042754 negative regulation of circadian rhythm
GO:0045892 negative regulation of transcription, DNA-templated
GO:0048511 rhythmic process
GO:0051567 histone H3-K9 methylation
Cellular Component
GO:0000775 chromosome, centromeric region
GO:0000785 chromatin
GO:0005634 nucleus
GO:0005720 nuclear heterochromatin
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000026646
View Gene Order
ENSBTAG00000010210
Not yet available
Pathways
NETPATH
REACTOME
KEGG
hsa00310
Lysine degradation pathway
INOH
PID NCI
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Hs.554883
RefSeq NM_001193424 NM_001193425 NM_001193426 NM_001193427 NM_024670 XM_006717503
HUGO
OMIM
CCDS CCDS53493 CCDS53494 CCDS7104
HPRD 07580
IMGT
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca