Version 5.4
| Mus musculus Gene: Maoa | |||||||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Summary | |||||||||||||||||||||||
| InnateDB Gene | IDBG-133557.6 | ||||||||||||||||||||||
| Last Modified | 2014-10-13 [Report errors or provide feedback] | ||||||||||||||||||||||
| Gene Symbol | Maoa | ||||||||||||||||||||||
| Gene Name | monoamine oxidase A | ||||||||||||||||||||||
| Synonyms | 1110061B18Rik; AA407771 | ||||||||||||||||||||||
| Species | Mus musculus | ||||||||||||||||||||||
| Ensembl Gene | ENSMUSG00000025037 | ||||||||||||||||||||||
| Encoded Proteins |
monoamine oxidase A
|
||||||||||||||||||||||
| Protein Structure | |||||||||||||||||||||||
| Useful resources | Stemformatics EHFPI ImmGen | ||||||||||||||||||||||
| Entrez Gene | |||||||||||||||||||||||
| Summary |
This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000189221:
This gene is one of two neighboring gene family members that encode mitochondrial enzymes which catalyze the oxidative deamination of amines, such as dopamine, norepinephrine, and serotonin. Mutation of this gene results in Brunner syndrome. This gene has also been associated with a variety of other psychiatric disorders, including antisocial behavior. Alternatively spliced transcript variants encoding multiple isoforms have been observed. [provided by RefSeq, Jul 2012] |
||||||||||||||||||||||
| Gene Information | |||||||||||||||||||||||
| Type | Protein coding | ||||||||||||||||||||||
| Genomic Location | Chromosome X:16619698-16687818 | ||||||||||||||||||||||
| Strand | Forward strand | ||||||||||||||||||||||
| Band | A1.2 | ||||||||||||||||||||||
| Transcripts |
|
||||||||||||||||||||||
| Interactions | |||||||||||||||||||||||
| Number of Interactions |
This gene and/or its encoded proteins are associated with 3 experimentally validated interaction(s) in this database.
They are also associated with 3 interaction(s) predicted by orthology.
|
||||||||||||||||||||||
| Gene Ontology | |||||||||||||||||||||||
Molecular Function |
|
||||||||||||||||||||||
| Biological Process |
|
||||||||||||||||||||||
| Cellular Component |
|
||||||||||||||||||||||
| Orthologs | |||||||||||||||||||||||
|
Species
Homo sapiens
Bos taurus
|
Gene ID
Gene Order
Not yet available
|
||||||||||||||||||||||
| Pathways | |||||||||||||||||||||||
| NETPATH | |||||||||||||||||||||||
| REACTOME |
Phase 1 - Functionalization of compounds pathway
Serotonin clearance from the synaptic cleft pathway
Dopamine clearance from the synaptic cleft pathway
Metabolism pathway
Metabolism of serotonin pathway
Neurotransmitter Clearance In The Synaptic Cleft pathway
Biogenic amines are oxidatively deaminated to aldehydes by MAOA and MAOB pathway
Enzymatic degradation of dopamine by COMT pathway
Enzymatic degradation of Dopamine by monoamine oxidase pathway
Neurotransmitter Release Cycle pathway
Norepinephrine Neurotransmitter Release Cycle pathway
Neuronal System pathway
Biological oxidations pathway
Transmission across Chemical Synapses pathway
Amine Oxidase reactions pathway
|
||||||||||||||||||||||
| KEGG |
Tyrosine metabolism pathway
Histidine metabolism pathway
Glycine, serine and threonine metabolism pathway
Arginine and proline metabolism pathway
Tryptophan metabolism pathway
Phenylalanine metabolism pathway
Drug metabolism pathway
|
||||||||||||||||||||||
| INOH | |||||||||||||||||||||||
| PID NCI | |||||||||||||||||||||||
| Pathway Predictions based on Human Orthology Data | |||||||||||||||||||||||
| NETPATH | |||||||||||||||||||||||
| REACTOME |
Biogenic amines are oxidatively deaminated to aldehydes by MAOA and MAOB pathway
Norepinephrine Neurotransmitter Release Cycle pathway
Enzymatic degradation of Dopamine by monoamine oxidase pathway
Metabolism of serotonin pathway
Enzymatic degradation of dopamine by COMT pathway
Dopamine clearance from the synaptic cleft pathway
Neurotransmitter Clearance In The Synaptic Cleft pathway
Neuronal System pathway
Amine Oxidase reactions pathway
Serotonin clearance from the synaptic cleft pathway
Transmission across Chemical Synapses pathway
Neurotransmitter Release Cycle pathway
Metabolism pathway
Biological oxidations pathway
Phase 1 - Functionalization of compounds pathway
Neurotransmitter Clearance In The Synaptic Cleft pathway
Neurotransmitter Release Cycle pathway
Dopamine clearance from the synaptic cleft pathway
Enzymatic degradation of dopamine by COMT pathway
Transmission across Chemical Synapses pathway
Biogenic amines are oxidatively deaminated to aldehydes by MAOA and MAOB pathway
Phase 1 - Functionalization of compounds pathway
Biological oxidations pathway
Amine Oxidase reactions pathway
Enzymatic degradation of Dopamine by monoamine oxidase pathway
Neuronal System pathway
Metabolism pathway
Norepinephrine Neurotransmitter Release Cycle pathway
Metabolism of serotonin pathway
Serotonin clearance from the synaptic cleft pathway
|
||||||||||||||||||||||
| KEGG |
Histidine metabolism pathway
Phenylalanine metabolism pathway
Arginine and proline metabolism pathway
Glycine, serine and threonine metabolism pathway
Tryptophan metabolism pathway
Tyrosine metabolism pathway
Drug metabolism pathway
|
||||||||||||||||||||||
| INOH |
Tryptophan degradation pathway
Phenylalanine degradation pathway
Arginine Proline metabolism pathway
Tyrosine metabolism pathway
Glycine Serine metabolism pathway
Histidine degradation pathway
|
||||||||||||||||||||||
| PID NCI | |||||||||||||||||||||||
| Cross-References | |||||||||||||||||||||||
| SwissProt | |||||||||||||||||||||||
| TrEMBL | |||||||||||||||||||||||
| UniProt Splice Variant | |||||||||||||||||||||||
| Entrez Gene | |||||||||||||||||||||||
| UniGene | Mm.21108 Mm.400097 | ||||||||||||||||||||||
| RefSeq | NM_173740 | ||||||||||||||||||||||
| OMIM | |||||||||||||||||||||||
| CCDS | CCDS30033 | ||||||||||||||||||||||
| HPRD | |||||||||||||||||||||||
| IMGT | |||||||||||||||||||||||
| MGI ID | |||||||||||||||||||||||
| MGI Symbol | |||||||||||||||||||||||
| EMBL | |||||||||||||||||||||||
| GenPept | |||||||||||||||||||||||
| RNA Seq Atlas | |||||||||||||||||||||||