Mus musculus Gene: Ntan1
Summary
InnateDB Gene IDBG-134144.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Ntan1
Gene Name N-terminal Asn amidase
Synonyms
Species Mus musculus
Ensembl Gene ENSMUSG00000022681
Encoded Proteins
N-terminal Asn amidase
N-terminal Asn amidase
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000157045:
The protein encoded by this gene functions in a step-wise process of protein degradation through the N-end rule pathway. This protein acts as a tertiary destabilizing enzyme that deamidates N-terminal L-Asn residues on proteins to produce N-terminal L-Asp. L-Asp substrates are subsequently conjugated to L-Arg, which is recognized by specific E3 ubiquitin ligases and targeted to the proteasome. Pseudogenes of this gene are located on the long arms of chromosomes 8, 10 and 12. Alternative splicing results in multiple transcript variants that encode different protein isoforms. [provided by RefSeq, Jul 2012]
Gene Information
Type Protein coding
Genomic Location Chromosome 16:13819251-13835451
Strand Forward strand
Band A1
Transcripts
ENSMUST00000023362 ENSMUSP00000023362
ENSMUST00000115805 ENSMUSP00000111472
ENSMUST00000145248
ENSMUST00000124604
ENSMUST00000136618
ENSMUST00000141791
ENSMUST00000123849
ENSMUST00000139161
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
Gene Ontology

Molecular Function
Accession GO Term
GO:0008418 protein-N-terminal asparagine amidohydrolase activity
Biological Process
GO:0007613 memory
GO:0008152 metabolic process
GO:0008344 adult locomotory behavior
Cellular Component
GO:0005634 nucleus
GO:0005737 cytoplasm
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
Not yet available
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Mm.462122 Mm.472295
RefSeq NM_010946 XM_006521853
OMIM
CCDS CCDS27969
HPRD
IMGT
MGI ID
MGI Symbol
EMBL
GenPept
RNA Seq Atlas