Version 5.4
Mus musculus Gene: Cdk16
Summary
InnateDB Gene IDBG-135033.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Cdk16
Gene Name cyclin-dependent kinase 16
Synonyms Crk5; Pctaire1; Pctk1
Species Mus musculus
Ensembl Gene ENSMUSG00000031065
Encoded Proteins
IDBP-135035
cyclin-dependent kinase 16
IDBP-249805
cyclin-dependent kinase 16
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000102225:
The protein encoded by this gene belongs to the cdc2/cdkx subfamily of the ser/thr family of protein kinases. It may play a role in signal transduction cascades in terminally differentiated cells; in exocytosis; and in transport of secretory cargo from the endoplasmic reticulum. This gene is thought to escape X inactivation. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Dec 2009]
Gene Information
Type Protein coding
Genomic Location Chromosome X:20687954-20699880
Strand Forward strand
Band A1.3
Transcripts
ENSMUST00000033380 ENSMUSP00000033380
ENSMUST00000115364 ENSMUSP00000111021
ENSMUST00000132365
ENSMUST00000146259
ENSMUST00000122944
ENSMUST00000125035
ENSMUST00000148757
ENSMUST00000129914
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
They are also associated with 15 interaction(s) predicted by orthology.
Experimentally validated
Total 1 [view]
Protein-Protein 1 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 15 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0004672 protein kinase activity
GO:0004674 protein serine/threonine kinase activity
GO:0004693 cyclin-dependent protein serine/threonine kinase activity
GO:0004713 protein tyrosine kinase activity
GO:0005515 protein binding
GO:0005524 ATP binding
GO:0016772 transferase activity, transferring phosphorus-containing groups
Biological Process
GO:0006468 protein phosphorylation
GO:0006887 exocytosis
GO:0007049 cell cycle
GO:0007283 spermatogenesis
GO:0030252 growth hormone secretion
GO:0031175 neuron projection development
GO:0061178 regulation of insulin secretion involved in cellular response to glucose stimulus
Cellular Component
GO:0005737 cytoplasm
GO:0005886 plasma membrane
GO:0008021 synaptic vesicle
GO:0015630 microtubule cytoskeleton
GO:0030054 cell junction
GO:0030133 transport vesicle
GO:0031234 extrinsic component of cytoplasmic side of plasma membrane
GO:0043005 neuron projection
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000102225
View Gene Order
ENSBTAG00000016769
Not yet available
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Mm.102574 Mm.392081 Mm.411044
RefSeq NM_011049 XM_006527570
OMIM
CCDS CCDS30045
HPRD
IMGT
MGI ID
MGI Symbol
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca