Version 5.4
Mus musculus Gene: Stau2
Summary
InnateDB Gene IDBG-135149.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Stau2
Gene Name staufen (RNA binding protein) homolog 2 (Drosophila)
Synonyms
Species Mus musculus
Ensembl Gene ENSMUSG00000025920
Encoded Proteins
IDBP-135151
staufen (RNA binding protein) homolog 2 (Drosophila)
IDBP-135153
staufen (RNA binding protein) homolog 2 (Drosophila)
IDBP-249811
staufen (RNA binding protein) homolog 2 (Drosophila)
IDBP-531812
staufen (RNA binding protein) homolog 2 (Drosophila)
IDBP-540332
staufen (RNA binding protein) homolog 2 (Drosophila)
IDBP-531780
staufen (RNA binding protein) homolog 2 (Drosophila)
IDBP-538811
staufen (RNA binding protein) homolog 2 (Drosophila)
IDBP-535268
staufen (RNA binding protein) homolog 2 (Drosophila)
IDBP-536739
staufen (RNA binding protein) homolog 2 (Drosophila)
IDBP-536392
staufen (RNA binding protein) homolog 2 (Drosophila)
IDBP-535757
staufen (RNA binding protein) homolog 2 (Drosophila)
IDBP-533705
staufen (RNA binding protein) homolog 2 (Drosophila)
IDBP-540313
staufen (RNA binding protein) homolog 2 (Drosophila)
IDBP-533137
staufen (RNA binding protein) homolog 2 (Drosophila)
IDBP-531796
staufen (RNA binding protein) homolog 2 (Drosophila)
IDBP-539127
staufen (RNA binding protein) homolog 2 (Drosophila)
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000040341:
Staufen homolog 2 is a member of the family of double-stranded RNA (dsRNA)-binding proteins involved in the transport and/or localization of mRNAs to different subcellular compartments and/or organelles. These proteins are characterized by the presence of multiple dsRNA-binding domains which are required to bind RNAs having double-stranded secondary structures. Staufen homolog 2 shares 48.5% and 59.9% similarity with drosophila and human staufen, respectively. The exact function of Staufen homolog 2 is not known, but since it contains 3 copies of conserved dsRNA binding domain, it could be involved in double-stranded RNA binding events. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Aug 2009]
Gene Information
Type Protein coding
Genomic Location Chromosome 1:16228674-16520112
Strand Reverse strand
Band A3
Transcripts
ENSMUST00000054668 ENSMUSP00000053190
ENSMUST00000027052 ENSMUSP00000027052
ENSMUST00000115360
ENSMUST00000115359 ENSMUSP00000111016
ENSMUST00000162751 ENSMUSP00000124505
ENSMUST00000162627 ENSMUSP00000123781
ENSMUST00000162435 ENSMUSP00000123827
ENSMUST00000159558 ENSMUSP00000125726
ENSMUST00000128957 ENSMUSP00000122410
ENSMUST00000131257 ENSMUSP00000121410
ENSMUST00000162007 ENSMUSP00000124303
ENSMUST00000127420 ENSMUSP00000122116
ENSMUST00000149320 ENSMUSP00000118489
ENSMUST00000151888 ENSMUSP00000125473
ENSMUST00000153966 ENSMUSP00000117537
ENSMUST00000145092 ENSMUSP00000115041
ENSMUST00000144138 ENSMUSP00000119130
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 7 interaction(s) predicted by orthology.
Predicted by orthology
Total 7 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003725 double-stranded RNA binding
Biological Process
GO:0006810 transport
Cellular Component
GO:0005730 nucleolus
GO:0005783 endoplasmic reticulum
GO:0005874 microtubule
Orthologs
Species
Homo sapiens
Gene ID
Gene Order
ENSG00000040341
View Gene Order
Cross-References
SwissProt Q8CJ67
TrEMBL E0CZD3 E2QRQ3
UniProt Splice Variant
Entrez Gene 29819
UniGene Mm.216257 Mm.398510 Mm.401175
RefSeq NM_001111272 NM_025303 XM_006495527 XM_006495528 XM_006495529 XM_006495531 XM_006495532 XM_006495533
OMIM
CCDS CCDS14831 CCDS48223
HPRD
IMGT
MGI ID MGI:1352508
MGI Symbol Stau2
EMBL AC115952 AC116695 AC162448 AC167117 AF459099 AF459100 AK015087 AK028390 BC010300 BC025118
GenPept AAH10300 AAH25118 AAN37928 AAN37929 BAB29708 BAC25926
RNA Seq Atlas 29819

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca