Version 5.4
Mus musculus Gene: Btn2a2
Summary
InnateDB Gene IDBG-135856.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Btn2a2
Gene Name butyrophilin, subfamily 2, member A2
Synonyms
Species Mus musculus
Ensembl Gene ENSMUSG00000053216
Encoded Proteins
IDBP-135858
butyrophilin, subfamily 2, member A2
IDBP-260285
butyrophilin, subfamily 2, member A2
IDBP-260287
butyrophilin, subfamily 2, member A2
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000124508:
Butyrophilin is the major protein associated with fat droplets in the milk. This gene is a member of the BTN2 subfamily of genes, which encode proteins belonging to the butyrophilin protein family. The gene is located in a cluster on chromosome 6, consisting of seven genes belonging to the expanding B7/butyrophilin-like group, a subset of the immunoglobulin gene superfamily. The encoded protein is a type I receptor glycoprotein involved in lipid, fatty-acid and sterol metabolism. Several alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2010]
Gene Information
Type Protein coding
Genomic Location Chromosome 13:23477676-23488857
Strand Reverse strand
Band A3.1
Transcripts
ENSMUST00000041541 ENSMUSP00000048251
ENSMUST00000110433 ENSMUSP00000106063
ENSMUST00000110432 ENSMUSP00000106062
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Predicted by orthology
Total 1 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003674 molecular_function
GO:0005515 protein binding
Biological Process
GO:0031324 negative regulation of cellular metabolic process
GO:0046007 negative regulation of activated T cell proliferation
GO:0050710 negative regulation of cytokine secretion
Cellular Component
GO:0005575 cellular_component
GO:0016021 integral component of membrane
Orthologs
Species
Homo sapiens
Gene ID
Gene Order
ENSG00000124508
View Gene Order
Cross-References
SwissProt
TrEMBL I7HIQ7
UniProt Splice Variant
Entrez Gene 238555
UniGene Mm.129668
RefSeq NM_001289615 NM_175938 XM_006516664
OMIM
CCDS CCDS36619
HPRD
IMGT
MGI ID MGI:3606486
MGI Symbol Btn2a2
EMBL AL714025
GenPept
RNA Seq Atlas 238555

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca