Mus musculus Gene: Ifrd1 | |||||||||||||||||||||||
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Summary | |||||||||||||||||||||||
InnateDB Gene | IDBG-136330.6 | ||||||||||||||||||||||
Last Modified | 2014-10-13 [Report errors or provide feedback] | ||||||||||||||||||||||
Gene Symbol | Ifrd1 | ||||||||||||||||||||||
Gene Name | interferon-related developmental regulator 1 | ||||||||||||||||||||||
Synonyms | Ifnl; PC4; Tis7 | ||||||||||||||||||||||
Species | Mus musculus | ||||||||||||||||||||||
Ensembl Gene | ENSMUSG00000001627 | ||||||||||||||||||||||
Encoded Proteins |
interferon-related developmental regulator 1
interferon-related developmental regulator 1
interferon-related developmental regulator 1
interferon-related developmental regulator 1
interferon-related developmental regulator 1
interferon-related developmental regulator 1
interferon-related developmental regulator 1
interferon-related developmental regulator 1
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Protein Structure | |||||||||||||||||||||||
Useful resources | Stemformatics EHFPI ImmGen | ||||||||||||||||||||||
InnateDB Annotation from Orthologs | |||||||||||||||||||||||
Summary |
[Homo sapiens] Human papillomaviruses impair the acetylation of NFκB/RelA K310 in keratinocytes by augmenting the expression of interferon-related developmental regulator 1 (IFRD1) in an EGFR-dependent manner.
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Entrez Gene | |||||||||||||||||||||||
Summary |
This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000006652:
This gene is an immediate early gene that encodes a protein related to interferon-gamma. This protein may function as a transcriptional co-activator/repressor that controls the growth and differentiation of specific cell types during embryonic development and tissue regeneration. Mutations in this gene are associated with sensory/motor neuropathy with ataxia. This gene may also be involved in modulating the pathogenesis of cystic fibrosis lung disease. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Oct 2010] |
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Gene Information | |||||||||||||||||||||||
Type | Protein coding | ||||||||||||||||||||||
Genomic Location | Chromosome 12:40201567-40248504 | ||||||||||||||||||||||
Strand | Reverse strand | ||||||||||||||||||||||
Band | B1 | ||||||||||||||||||||||
Transcripts | |||||||||||||||||||||||
Interactions | |||||||||||||||||||||||
Number of Interactions |
This gene and/or its encoded proteins are associated with 7 experimentally validated interaction(s) in this database.
They are also associated with 8 interaction(s) predicted by orthology.
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Gene Ontology | |||||||||||||||||||||||
Molecular Function |
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Biological Process |
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Cellular Component |
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Orthologs | |||||||||||||||||||||||
Species
Homo sapiens
Bos taurus
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Gene ID
Gene Order
Not yet available
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Cross-References | |||||||||||||||||||||||
SwissProt | |||||||||||||||||||||||
TrEMBL | |||||||||||||||||||||||
UniProt Splice Variant | |||||||||||||||||||||||
Entrez Gene | 15982 | ||||||||||||||||||||||
UniGene | Mm.168 | ||||||||||||||||||||||
RefSeq | NM_013562 | ||||||||||||||||||||||
OMIM | |||||||||||||||||||||||
CCDS | CCDS25893 | ||||||||||||||||||||||
HPRD | |||||||||||||||||||||||
IMGT | |||||||||||||||||||||||
MGI ID | MGI:1316717 | ||||||||||||||||||||||
MGI Symbol | Ifrd1 | ||||||||||||||||||||||
EMBL | |||||||||||||||||||||||
GenPept | |||||||||||||||||||||||
RNA Seq Atlas | 15982 | ||||||||||||||||||||||