Homo sapiens Gene: IFRD1 | |||||||||||||||||||||||
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Summary | |||||||||||||||||||||||
InnateDB Gene | IDBG-36786.6 | ||||||||||||||||||||||
Last Modified | 2014-10-13 [Report errors or provide feedback] | ||||||||||||||||||||||
Gene Symbol | IFRD1 | ||||||||||||||||||||||
Gene Name | interferon-related developmental regulator 1 | ||||||||||||||||||||||
Synonyms | PC4; TIS7 | ||||||||||||||||||||||
Species | Homo sapiens | ||||||||||||||||||||||
Ensembl Gene | ENSG00000006652 | ||||||||||||||||||||||
Encoded Proteins |
interferon-related developmental regulator 1
interferon-related developmental regulator 1
interferon-related developmental regulator 1
interferon-related developmental regulator 1
interferon-related developmental regulator 1
interferon-related developmental regulator 1
interferon-related developmental regulator 1
interferon-related developmental regulator 1
interferon-related developmental regulator 1
interferon-related developmental regulator 1
interferon-related developmental regulator 1
interferon-related developmental regulator 1
interferon-related developmental regulator 1
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Protein Structure | |||||||||||||||||||||||
Useful resources | Stemformatics EHFPI ImmGen | ||||||||||||||||||||||
InnateDB Annotation | |||||||||||||||||||||||
Summary |
Human papillomaviruses impair the acetylation of NFκB/RelA K310 in keratinocytes by augmenting the expression of interferon-related developmental regulator 1 (IFRD1) in an EGFR-dependent manner.
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Entrez Gene | |||||||||||||||||||||||
Summary |
This gene is an immediate early gene that encodes a protein related to interferon-gamma. This protein may function as a transcriptional co-activator/repressor that controls the growth and differentiation of specific cell types during embryonic development and tissue regeneration. Mutations in this gene are associated with sensory/motor neuropathy with ataxia. This gene may also be involved in modulating the pathogenesis of cystic fibrosis lung disease. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Oct 2010] |
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Gene Information | |||||||||||||||||||||||
Type | Protein coding | ||||||||||||||||||||||
Genomic Location | Chromosome 7:112422968-112481017 | ||||||||||||||||||||||
Strand | Forward strand | ||||||||||||||||||||||
Band | q31.1 | ||||||||||||||||||||||
Transcripts | |||||||||||||||||||||||
Interactions | |||||||||||||||||||||||
Number of Interactions |
This gene and/or its encoded proteins are associated with 16 experimentally validated interaction(s) in this database.
They are also associated with 5 interaction(s) predicted by orthology.
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Gene Ontology | |||||||||||||||||||||||
Molecular Function |
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Biological Process |
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Cellular Component |
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Orthologs | |||||||||||||||||||||||
Species
Mus musculus
Bos taurus
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Gene ID
Gene Order
Not yet available
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Cross-References | |||||||||||||||||||||||
SwissProt | |||||||||||||||||||||||
TrEMBL | |||||||||||||||||||||||
UniProt Splice Variant | |||||||||||||||||||||||
Entrez Gene | |||||||||||||||||||||||
UniGene | Hs.702661 Hs.709100 Hs.729518 Hs.7879 | ||||||||||||||||||||||
RefSeq | NM_001007245 NM_001197079 NM_001197080 NM_001550 | ||||||||||||||||||||||
HUGO | |||||||||||||||||||||||
OMIM | |||||||||||||||||||||||
CCDS | CCDS34736 CCDS56504 | ||||||||||||||||||||||
HPRD | 04612 | ||||||||||||||||||||||
IMGT | |||||||||||||||||||||||
EMBL | |||||||||||||||||||||||
GenPept | |||||||||||||||||||||||
RNA Seq Atlas | |||||||||||||||||||||||