Version 5.4
Bos taurus Gene: IFRD1
Summary
InnateDB Gene IDBG-632907.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol IFRD1
Gene Name interferon-related developmental regulator 1
Synonyms
Species Bos taurus
Ensembl Gene ENSBTAG00000010549
Encoded Proteins
IDBP-684578
interferon-related developmental regulator 1
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
InnateDB Annotation from Orthologs
Summary
PMID 26055519
[Homo sapiens] Human papillomaviruses impair the acetylation of NFκB/RelA K310 in keratinocytes by augmenting the expression of interferon-related developmental regulator 1 (IFRD1) in an EGFR-dependent manner.
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000006652:
This gene is an immediate early gene that encodes a protein related to interferon-gamma. This protein may function as a transcriptional co-activator/repressor that controls the growth and differentiation of specific cell types during embryonic development and tissue regeneration. Mutations in this gene are associated with sensory/motor neuropathy with ataxia. This gene may also be involved in modulating the pathogenesis of cystic fibrosis lung disease. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Oct 2010]
Gene Information
Type Protein coding
Genomic Location Chromosome 4:55872976-55896662
Strand Reverse strand
Band
Transcripts
ENSBTAT00000013950 ENSBTAP00000013950
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 10 interaction(s) predicted by orthology.
Predicted by orthology
Total 10 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005488 binding
Biological Process
GO:0007527 adult somatic muscle development
GO:0042692 muscle cell differentiation
Cellular Component
GO:0005634 nucleus
Orthologs
Species
Homo sapiens
Mus musculus
Gene ID
Gene Order
ENSG00000006652
View Gene Order
ENSMUSG00000001627
View Gene Order
Cross-References
SwissProt
TrEMBL F1MN39
UniProt Splice Variant
Entrez Gene 541283
UniGene Bt.14054
RefSeq NM_001034729
HUGO HGNC:5456
OMIM
CCDS
HPRD
IMGT
EMBL DAAA02010677
GenPept
RNA Seq Atlas 541283

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca