Mus musculus Gene: Slc22a2 | |||||||||||||||
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Summary | |||||||||||||||
InnateDB Gene | IDBG-136835.6 | ||||||||||||||
Last Modified | 2014-10-13 [Report errors or provide feedback] | ||||||||||||||
Gene Symbol | Slc22a2 | ||||||||||||||
Gene Name | solute carrier family 22 (organic cation transporter), member 2 | ||||||||||||||
Synonyms | Oct2; Orct2 | ||||||||||||||
Species | Mus musculus | ||||||||||||||
Ensembl Gene | ENSMUSG00000040966 | ||||||||||||||
Encoded Proteins |
solute carrier family 22 (organic cation transporter), member 2
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Protein Structure | |||||||||||||||
Useful resources | Stemformatics EHFPI ImmGen | ||||||||||||||
Entrez Gene | |||||||||||||||
Summary |
This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000112499:
Polyspecific organic cation transporters in the liver, kidney, intestine, and other organs are critical for elimination of many endogenous small organic cations as well as a wide array of drugs and environmental toxins. This gene is one of three similar cation transporter genes located in a cluster on chromosome 6. The encoded protein contains twelve putative transmembrane domains and is a plasma integral membrane protein. It is found primarily in the kidney, where it may mediate the first step in cation reabsorption. [provided by RefSeq, Jul 2008] |
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Gene Information | |||||||||||||||
Type | Protein coding | ||||||||||||||
Genomic Location | Chromosome 17:12584189-12628465 | ||||||||||||||
Strand | Forward strand | ||||||||||||||
Band | A1 | ||||||||||||||
Transcripts |
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Interactions | |||||||||||||||
Number of Interactions |
This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 7 interaction(s) predicted by orthology.
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Gene Ontology | |||||||||||||||
Molecular Function |
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Biological Process |
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Cellular Component |
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Orthologs | |||||||||||||||
Species
Homo sapiens
Bos taurus
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Gene ID
Gene Order
Not yet available
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Pathways | |||||||||||||||
NETPATH | |||||||||||||||
REACTOME |
Transport of glucose and other sugars, bile salts and organic acids, metal ions and amine compounds pathway
SLC-mediated transmembrane transport pathway
Metabolism pathway
Neurotransmitter Clearance In The Synaptic Cleft pathway
Na+/Cl- dependent neurotransmitter transporters pathway
Abacavir transport and metabolism pathway
Abacavir transmembrane transport pathway
Neurotransmitter Release Cycle pathway
Norepinephrine Neurotransmitter Release Cycle pathway
Transmembrane transport of small molecules pathway
Organic cation/anion/zwitterion transport pathway
Neuronal System pathway
Organic cation transport pathway
Transmission across Chemical Synapses pathway
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KEGG | |||||||||||||||
INOH | |||||||||||||||
PID NCI | |||||||||||||||
Pathway Predictions based on Human Orthology Data | |||||||||||||||
NETPATH | |||||||||||||||
REACTOME |
Organic cation transport pathway
Na+/Cl- dependent neurotransmitter transporters pathway
Transport of glucose and other sugars, bile salts and organic acids, metal ions and amine compounds pathway
Abacavir transmembrane transport pathway
Norepinephrine Neurotransmitter Release Cycle pathway
Neurotransmitter Clearance In The Synaptic Cleft pathway
Transmembrane transport of small molecules pathway
Neuronal System pathway
Organic cation/anion/zwitterion transport pathway
Transmission across Chemical Synapses pathway
Neurotransmitter Release Cycle pathway
Abacavir transport and metabolism pathway
Metabolism pathway
SLC-mediated transmembrane transport pathway
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KEGG | |||||||||||||||
INOH | |||||||||||||||
PID NCI | |||||||||||||||
Cross-References | |||||||||||||||
SwissProt | O70577 | ||||||||||||||
TrEMBL | |||||||||||||||
UniProt Splice Variant | |||||||||||||||
Entrez Gene | 20518 | ||||||||||||||
UniGene | Mm.17322 | ||||||||||||||
RefSeq | NM_013667 | ||||||||||||||
OMIM | |||||||||||||||
CCDS | CCDS28392 | ||||||||||||||
HPRD | |||||||||||||||
IMGT | |||||||||||||||
MGI ID | MGI:1335072 | ||||||||||||||
MGI Symbol | Slc22a2 | ||||||||||||||
EMBL | AF481054 AJ006036 AK052658 BC015250 BC069911 | ||||||||||||||
GenPept | AAH15250 AAH69911 AAM22158 BAC35086 CAA06827 | ||||||||||||||
RNA Seq Atlas | 20518 | ||||||||||||||