Version 5.4
Mus musculus Gene: Kcnq5
Summary
InnateDB Gene IDBG-137293.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Kcnq5
Gene Name potassium voltage-gated channel, subfamily Q, member 5
Synonyms
Species Mus musculus
Ensembl Gene ENSMUSG00000028033
Encoded Proteins
IDBP-137295
potassium voltage-gated channel, subfamily Q, member 5
IDBP-249942
potassium voltage-gated channel, subfamily Q, member 5
IDBP-622761
potassium voltage-gated channel, subfamily Q, member 5
IDBP-622764
potassium voltage-gated channel, subfamily Q, member 5
IDBP-622766
potassium voltage-gated channel, subfamily Q, member 5
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000185760:
This gene is a member of the KCNQ potassium channel gene family that is differentially expressed in subregions of the brain and in skeletal muscle. The protein encoded by this gene yields currents that activate slowly with depolarization and can form heteromeric channels with the protein encoded by the KCNQ3 gene. Currents expressed from this protein have voltage dependences and inhibitor sensitivities in common with M-currents. They are also inhibited by M1 muscarinic receptor activation. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, May 2009]
Gene Information
Type Protein coding
Genomic Location Chromosome 1:21398403-21961942
Strand Reverse strand
Band A4
Transcripts
ENSMUST00000029667 ENSMUSP00000029667
ENSMUST00000115300 ENSMUSP00000110955
ENSMUST00000115299
ENSMUST00000134505
ENSMUST00000173058 ENSMUSP00000134166
ENSMUST00000174183 ENSMUSP00000134389
ENSMUST00000173404 ENSMUSP00000134076
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 3 interaction(s) predicted by orthology.
Predicted by orthology
Total 3 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005216 ion channel activity
GO:0005249 voltage-gated potassium channel activity
GO:0005251 delayed rectifier potassium channel activity
Biological Process
GO:0006811 ion transport
GO:0006813 potassium ion transport
GO:0034765 regulation of ion transmembrane transport
GO:0055085 transmembrane transport
GO:0071805 potassium ion transmembrane transport
Cellular Component
GO:0008076 voltage-gated potassium channel complex
GO:0016020 membrane
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000185760
View Gene Order
ENSBTAG00000007791
Not yet available
Pathways
NETPATH
REACTOME
REACT_202800
Potassium Channels pathway
REACT_259290
Neuronal System pathway
REACT_199077
Voltage gated Potassium channels pathway
KEGG
INOH
PID NCI
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
REACT_75770
Voltage gated Potassium channels pathway
REACT_13685
Neuronal System pathway
REACT_75908
Potassium Channels pathway
KEGG
INOH
PID NCI
Cross-References
SwissProt
TrEMBL G3UYP4 Q9CTU2
UniProt Splice Variant
Entrez Gene 226922
UniGene Mm.336519 Mm.396950
RefSeq NM_001160139 NM_023872
OMIM
CCDS CCDS35525 CCDS48230
HPRD
IMGT
MGI ID MGI:1924937
MGI Symbol Kcnq5
EMBL AC110269 AC115920 AC125483 AC131088 AK020325
GenPept BAB32071
RNA Seq Atlas 226922

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca