Version 5.4
Mus musculus Gene: Nova1
Summary
InnateDB Gene IDBG-137550.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Nova1
Gene Name neuro-oncological ventral antigen 1
Synonyms
Species Mus musculus
Ensembl Gene ENSMUSG00000021047
Encoded Proteins
IDBP-137552
neuro-oncological ventral antigen 1
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000139910:
This gene encodes a neuron-specific RNA-binding protein, a member of the Nova family of paraneoplastic disease antigens, that is recognized and inhibited by paraneoplastic antibodies. These antibodies are found in the sera of patients with paraneoplastic opsoclonus-ataxia, breast cancer, and small cell lung cancer. Alternatively spliced transcripts encoding distinct isoforms have been described. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 12:46694517-46818775
Strand Reverse strand
Band B3
Transcripts
ENSMUST00000021438 ENSMUSP00000021438
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 164 experimentally validated interaction(s) in this database.
They are also associated with 5 interaction(s) predicted by orthology.
Experimentally validated
Total 164 [view]
Protein-Protein 4 [view]
Protein-DNA 0
Protein-RNA 160 [view]
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 5 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003723 RNA binding
GO:0003729 mRNA binding
GO:0044822 poly(A) RNA binding
Biological Process
GO:0000398 mRNA splicing, via spliceosome
GO:0051252 regulation of RNA metabolic process
Cellular Component
GO:0005634 nucleus
GO:0005730 nucleolus
GO:0043231 intracellular membrane-bounded organelle
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000139910
View Gene Order
ENSBTAG00000002170
Not yet available
Cross-References
SwissProt Q9JKN6
TrEMBL A3KMK7
UniProt Splice Variant
Entrez Gene 664883
UniGene Mm.247195 Mm.402774
RefSeq NM_021361 XM_006516151 XM_006516152 XM_006516153
OMIM
CCDS CCDS49058
HPRD
IMGT
MGI ID MGI:104297
MGI Symbol Nova1
EMBL AC108802 AC156636 AF232828 AK047565 BC132210 BC132354
GenPept AAF35907 AAI32211 AAI32355 BAC33088
RNA Seq Atlas 664883

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca