Version 5.4
Mus musculus Gene: Smap1
Summary
InnateDB Gene IDBG-138076.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Smap1
Gene Name stromal membrane-associated protein 1
Synonyms 1700056O10Rik; 4921514B13Rik; 4921525H11Rik; AI462175
Species Mus musculus
Ensembl Gene ENSMUSG00000026155
Encoded Proteins
IDBP-138078
stromal membrane-associated protein 1
IDBP-531888
stromal membrane-associated protein 1
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000112305:
The protein encoded by this gene is similar to the mouse stromal membrane-associated protein-1. This similarity suggests that this human gene product is also a type II membrane glycoprotein involved in the erythropoietic stimulatory activity of stromal cells. Alternate splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 1:23844846-23922317
Strand Reverse strand
Band A5
Transcripts
ENSMUST00000027339 ENSMUSP00000027339
ENSMUST00000149737
ENSMUST00000136506
ENSMUST00000129254 ENSMUSP00000117875
ENSMUST00000148710
ENSMUST00000141330
ENSMUST00000133398
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 2 experimentally validated interaction(s) in this database.
They are also associated with 6 interaction(s) predicted by orthology.
Experimentally validated
Total 2 [view]
Protein-Protein 2 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 6 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0008060 ARF GTPase activator activity
GO:0008270 zinc ion binding
GO:0030276 clathrin binding
Biological Process
GO:0032312 regulation of ARF GTPase activity
GO:0043547 positive regulation of GTPase activity
GO:0045648 positive regulation of erythrocyte differentiation
GO:2000369 regulation of clathrin-mediated endocytosis
Cellular Component
GO:0005737 cytoplasm
GO:0005886 plasma membrane
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000112305
View Gene Order
ENSBTAG00000038190
Not yet available
Pathways
NETPATH
REACTOME
KEGG
mmu04144
Endocytosis pathway
INOH
PID NCI
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
KEGG
hsa04144
Endocytosis pathway
INOH
PID NCI
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Mm.329963
RefSeq NM_001290683 NM_028534 XM_006496363
OMIM
CCDS CCDS14851 CCDS69870
HPRD
IMGT
MGI ID
MGI Symbol
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca