Version 5.4
Mus musculus Gene: Lrrc16a
Summary
InnateDB Gene IDBG-138221.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Lrrc16a
Gene Name leucine rich repeat containing 16A
Synonyms 1110037D04Rik; AI425970; CARMIL; D130057M20; Lrrc16
Species Mus musculus
Ensembl Gene ENSMUSG00000021338
Encoded Proteins
IDBP-138227
leucine rich repeat containing 16A
IDBP-260356
leucine rich repeat containing 16A
IDBP-619757
leucine rich repeat containing 16A
IDBP-533498
leucine rich repeat containing 16A
IDBP-619758
leucine rich repeat containing 16A
IDBP-619759
leucine rich repeat containing 16A
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000079691:
Gene Information
Type Protein coding
Genomic Location Chromosome 13:24012344-24280795
Strand Reverse strand
Band A3.1
Transcripts
ENSMUST00000072889 ENSMUSP00000072662
ENSMUST00000110398 ENSMUSP00000106028
ENSMUST00000125901 ENSMUSP00000126522
ENSMUST00000151566 ENSMUSP00000120971
ENSMUST00000147261
ENSMUST00000142171
ENSMUST00000128416
ENSMUST00000125420
ENSMUST00000144159
ENSMUST00000140042 ENSMUSP00000127121
ENSMUST00000123076 ENSMUSP00000130100
ENSMUST00000136517
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
They are also associated with 5 interaction(s) predicted by orthology.
Experimentally validated
Total 1 [view]
Protein-Protein 1 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 5 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0032403 protein complex binding
Biological Process
GO:0016477 cell migration
GO:0030032 lamellipodium assembly
GO:0030335 positive regulation of cell migration
GO:0030838 positive regulation of actin filament polymerization
GO:0031529 ruffle organization
GO:0046415 urate metabolic process
GO:0051496 positive regulation of stress fiber assembly
GO:0051638 barbed-end actin filament uncapping
GO:1900026 positive regulation of substrate adhesion-dependent cell spreading
GO:1902745 positive regulation of lamellipodium organization
GO:2000813 negative regulation of barbed-end actin filament capping
Cellular Component
GO:0005634 nucleus
GO:0005737 cytoplasm
GO:0030027 lamellipodium
GO:0031941 filamentous actin
GO:0070062 extracellular vesicular exosome
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000079691
View Gene Order
ENSBTAG00000016549
Not yet available
Pathways
NETPATH
REACTOME
REACT_224553
Hemostasis pathway
REACT_198649
Factors involved in megakaryocyte development and platelet production pathway
KEGG
INOH
PID NCI
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
REACT_24970
Factors involved in megakaryocyte development and platelet production pathway
REACT_604
Hemostasis pathway
KEGG
INOH
PID NCI
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Mm.211047 Mm.416277
RefSeq NM_026825 XM_006516742 XM_006516744 XM_006516745 XM_006516746 XM_006516747
OMIM
CCDS CCDS36621
HPRD
IMGT
MGI ID
MGI Symbol
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca