Mus musculus Gene: Pi4ka | |||||||||||||||||||||||
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Summary | |||||||||||||||||||||||
InnateDB Gene | IDBG-138500.6 | ||||||||||||||||||||||
Last Modified | 2014-10-13 [Report errors or provide feedback] | ||||||||||||||||||||||
Gene Symbol | Pi4ka | ||||||||||||||||||||||
Gene Name | phosphatidylinositol 4-kinase, catalytic, alpha polypeptide | ||||||||||||||||||||||
Synonyms | |||||||||||||||||||||||
Species | Mus musculus | ||||||||||||||||||||||
Ensembl Gene | ENSMUSG00000041720 | ||||||||||||||||||||||
Encoded Proteins |
phosphatidylinositol 4-kinase, catalytic, alpha polypeptide
phosphatidylinositol 4-kinase, catalytic, alpha polypeptide
phosphatidylinositol 4-kinase, catalytic, alpha polypeptide
phosphatidylinositol 4-kinase, catalytic, alpha polypeptide
phosphatidylinositol 4-kinase, catalytic, alpha polypeptide
phosphatidylinositol 4-kinase, catalytic, alpha polypeptide
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Protein Structure | |||||||||||||||||||||||
Useful resources | Stemformatics EHFPI ImmGen | ||||||||||||||||||||||
Entrez Gene | |||||||||||||||||||||||
Summary |
This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000241973:
This gene encodes a phosphatidylinositol (PI) 4-kinase which catalyzes the first committed step in the biosynthesis of phosphatidylinositol 4,5-bisphosphate. The mammalian PI 4-kinases have been classified into two types, II and III, based on their molecular mass, and modulation by detergent and adenosine. The protein encoded by this gene is a type III enzyme that is not inhibited by adenosine. Two transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Jul 2008] This gene encodes a phosphatidylinositol (PI) 4-kinase which catalyzes the first committed step in the biosynthesis of phosphatidylinositol 4,5-bisphosphate. The mammalian PI 4-kinases have been classified into two types, II and III, based on their molecular mass, and modulation by detergent and adenosine. The protein encoded by this gene is a type III enzyme that is not inhibited by adenosine. [provided by RefSeq, Sep 2014] |
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Gene Information | |||||||||||||||||||||||
Type | Protein coding | ||||||||||||||||||||||
Genomic Location | Chromosome 16:17280351-17406314 | ||||||||||||||||||||||
Strand | Reverse strand | ||||||||||||||||||||||
Band | A3 | ||||||||||||||||||||||
Transcripts | |||||||||||||||||||||||
Interactions | |||||||||||||||||||||||
Number of Interactions |
This gene and/or its encoded proteins are associated with 5 experimentally validated interaction(s) in this database.
They are also associated with 11 interaction(s) predicted by orthology.
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Gene Ontology | |||||||||||||||||||||||
Molecular Function |
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Biological Process |
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Cellular Component |
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Orthologs | |||||||||||||||||||||||
Species
Homo sapiens
Bos taurus
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Gene ID
Gene Order
Not yet available
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Pathways | |||||||||||||||||||||||
NETPATH | |||||||||||||||||||||||
REACTOME | |||||||||||||||||||||||
KEGG |
Phosphatidylinositol signaling system pathway
Inositol phosphate metabolism pathway
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INOH | |||||||||||||||||||||||
PID NCI | |||||||||||||||||||||||
Pathway Predictions based on Human Orthology Data | |||||||||||||||||||||||
NETPATH |
TCR pathway
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REACTOME |
Synthesis of PIPs at the ER membrane pathway
Synthesis of PIPs at the Golgi membrane pathway
Metabolism of lipids and lipoproteins pathway
PI Metabolism pathway
Phospholipid metabolism pathway
Metabolism pathway
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KEGG |
Inositol phosphate metabolism pathway
Phosphatidylinositol signaling system pathway
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INOH |
Inositol phosphate metabolism pathway
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PID NCI |
Integrins in angiogenesis
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Cross-References | |||||||||||||||||||||||
SwissProt | |||||||||||||||||||||||
TrEMBL | |||||||||||||||||||||||
UniProt Splice Variant | |||||||||||||||||||||||
Entrez Gene | |||||||||||||||||||||||
UniGene | Mm.400396 Mm.5718 | ||||||||||||||||||||||
RefSeq | NM_001001983 XM_006522034 XM_006522035 XM_006522036 XM_006522037 | ||||||||||||||||||||||
OMIM | |||||||||||||||||||||||
CCDS | CCDS37271 | ||||||||||||||||||||||
HPRD | |||||||||||||||||||||||
IMGT | |||||||||||||||||||||||
MGI ID | |||||||||||||||||||||||
MGI Symbol | |||||||||||||||||||||||
EMBL | |||||||||||||||||||||||
GenPept | |||||||||||||||||||||||
RNA Seq Atlas | |||||||||||||||||||||||