InnateDB: Systems Biology of the Innate Immune Response

Bos taurus Gene: PI4KA

Summary

InnateDB Gene

IDBG-637608.3

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

PI4KA

Gene Name

phosphatidylinositol 4-kinase alpha

Synonyms

PIK4CA

Species

Bos taurus

Ensembl Gene

ENSBTAG00000013971

Encoded Proteins

IDBP-689670

phosphatidylinositol 4-kinase alpha

Protein Structure

Useful resources

Stemformatics EHFPI ImmGen

Entrez Gene

Summary

This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000241973:
This gene encodes a phosphatidylinositol (PI) 4-kinase which catalyzes the first committed step in the biosynthesis of phosphatidylinositol 4,5-bisphosphate. The mammalian PI 4-kinases have been classified into two types, II and III, based on their molecular mass, and modulation by detergent and adenosine. The protein encoded by this gene is a type III enzyme that is not inhibited by adenosine. Two transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Jul 2008]
This gene encodes a phosphatidylinositol (PI) 4-kinase which catalyzes the first committed step in the biosynthesis of phosphatidylinositol 4,5-bisphosphate. The mammalian PI 4-kinases have been classified into two types, II and III, based on their molecular mass, and modulation by detergent and adenosine. The protein encoded by this gene is a type III enzyme that is not inhibited by adenosine. [provided by RefSeq, Sep 2014]

Gene Information

Type

Protein coding

Genomic Location

Chromosome 17:74200828-74260366

Strand

Reverse strand

Band

Transcripts

ENSBTAT00000018572

ENSBTAP00000018572

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 13 interaction(s) predicted by orthology.

Predicted by orthology
Total	13 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0004430	1-phosphatidylinositol 4-kinase activity
GO:0005488	binding
GO:0005515	protein binding
GO:0016301	kinase activity
GO:0016740	transferase activity
GO:0016772	transferase activity, transferring phosphorus-containing groups
GO:0016773	phosphotransferase activity, alcohol group as acceptor