Version 5.4
Homo sapiens Gene: VIPAS39
Summary
InnateDB Gene IDBG-13870.7
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol VIPAS39
Gene Name VPS33B interacting protein, apical-basolateral polarity regulator, spe-39 homolog
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000151445
Encoded Proteins
IDBP-13872
chromosome 14 open reading frame 133
IDBP-13874
chromosome 14 open reading frame 133
IDBP-374873
chromosome 14 open reading frame 133
IDBP-587888
chromosome 14 open reading frame 133
IDBP-584746
chromosome 14 open reading frame 133
IDBP-598175
chromosome 14 open reading frame 133
IDBP-599632
chromosome 14 open reading frame 133
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene encodes a protein involved in the sorting of lysosomal proteins. Mutations in this gene are associated with ARCS2 (arthrogryposis, renal dysfunction, and cholestasis-2). Alternative splicing results in multiple transcript variants.[provided by RefSeq, Jul 2010]
Gene Information
Type Protein coding
Genomic Location Chromosome 14:77426675-77457952
Strand Reverse strand
Band q24.3
Transcripts
ENST00000343765 ENSP00000339122
ENST00000327028 ENSP00000313098
ENST00000448935 ENSP00000404815
ENST00000553888 ENSP00000452181
ENST00000557658 ENSP00000452191
ENST00000556412 ENSP00000451857
ENST00000553576
ENST00000553691
ENST00000555854
ENST00000557466 ENSP00000452176
ENST00000556909
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 21 experimentally validated interaction(s) in this database.
Experimentally validated
Total 21 [view]
Protein-Protein 20 [view]
Protein-DNA 1 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
Biological Process
GO:0006351 transcription, DNA-templated
GO:0006355 regulation of transcription, DNA-templated
GO:0006886 intracellular protein transport
GO:0007283 spermatogenesis
GO:0008333 endosome to lysosome transport
GO:0030154 cell differentiation
Cellular Component
GO:0005737 cytoplasm
GO:0005769 early endosome
GO:0005770 late endosome
GO:0016023 cytoplasmic membrane-bounded vesicle
GO:0030897 HOPS complex
GO:0055037 recycling endosome
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000021038
View Gene Order
ENSBTAG00000020475
Not yet available
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Hs.16157
RefSeq NM_001193314 NM_001193315 NM_001193316 NM_001193317 NM_022067
HUGO
OMIM
CCDS CCDS53905 CCDS9862
HPRD 10710
IMGT
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca