Version 5.4
Mus musculus Gene: Akap7
Summary
InnateDB Gene IDBG-139548.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Akap7
Gene Name A kinase (PRKA) anchor protein 7
Synonyms
Species Mus musculus
Ensembl Gene ENSMUSG00000039166
Encoded Proteins
IDBP-139552
A kinase (PRKA) anchor protein 7
IDBP-139554
A kinase (PRKA) anchor protein 7
IDBP-139556
A kinase (PRKA) anchor protein 7
IDBP-714396
IDBP-712898
IDBP-711702
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000118507:
This gene encodes a member of the A-kinase anchoring protein (AKAP) family, a group of functionally related proteins that bind to a regulatory subunit (RII) of cAMP-dependent protein kinase A (PKA) and target the enzyme to specific subcellular compartments. AKAPs have a common RII-binding domain, but contain different targeting motifs responsible for directing PKA to distinct intracellular locations. Three alternatively spliced transcript variants encoding different isoforms have been described.[provided by RefSeq, Apr 2011]
Gene Information
Type Protein coding
Genomic Location Chromosome 10:25169090-25307870
Strand Reverse strand
Band A4
Transcripts
ENSMUST00000100012 ENSMUSP00000097590
ENSMUST00000041984 ENSMUSP00000043624
ENSMUST00000095779 ENSMUSP00000093455
ENSMUST00000175979
ENSMUST00000176231 ENSMUSP00000135433
ENSMUST00000176258 ENSMUSP00000135037
ENSMUST00000177124 ENSMUSP00000135137
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 2 experimentally validated interaction(s) in this database.
They are also associated with 4 interaction(s) predicted by orthology.
Experimentally validated
Total 2 [view]
Protein-Protein 2 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 4 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0000166 nucleotide binding
GO:0003824 catalytic activity
GO:0005515 protein binding
GO:0019901 protein kinase binding
GO:0034237 protein kinase A regulatory subunit binding
GO:0051018 protein kinase A binding
Biological Process
GO:0007178 transmembrane receptor protein serine/threonine kinase signaling pathway
GO:0008104 protein localization
GO:0008150 biological_process
GO:0008152 metabolic process
Cellular Component
GO:0005634 nucleus
GO:0005737 cytoplasm
GO:0005829 cytosol
GO:0016328 lateral plasma membrane
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000118507
View Gene Order
ENSBTAG00000000240
Not yet available
Cross-References
SwissProt Q7TN79
TrEMBL H3BJL8 H3BKK9 Q8BVR3
UniProt Splice Variant
Entrez Gene 432442
UniGene Mm.487103
RefSeq NM_018747 XM_006512786 XM_006512795
OMIM
CCDS CCDS23753
HPRD
IMGT
MGI ID MGI:1859150
MGI Symbol Akap7
EMBL AC153549 AC153550 AK076839 AY301068
GenPept AAP55205 BAC36503
RNA Seq Atlas 432442

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca