Version 5.4
Homo sapiens Gene: VPS53
Summary
InnateDB Gene IDBG-13990.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol VPS53
Gene Name vacuolar protein sorting 53 homolog (S. cerevisiae)
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000141252
Encoded Proteins
IDBP-13994
vacuolar protein sorting 53 homolog (S. cerevisiae)
IDBP-13998
vacuolar protein sorting 53 homolog (S. cerevisiae)
IDBP-292446
vacuolar protein sorting 53 homolog (S. cerevisiae)
IDBP-360767
vacuolar protein sorting 53 homolog (S. cerevisiae)
IDBP-762540
IDBP-763037
IDBP-758796
IDBP-761082
IDBP-761293
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene encodes a protein with sequence similarity to the yeast Vps53p protein. Vps53p is involved in retrograde vesicle trafficking in late Golgi. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 17:508668-721717
Strand Reverse strand
Band p13.3
Transcripts
ENST00000389040 ENSP00000373692
ENST00000291074 ENSP00000291074
ENST00000401468 ENSP00000384294
ENST00000437048 ENSP00000401435
ENST00000541903
ENST00000572607
ENST00000570510
ENST00000572334
ENST00000570359
ENST00000576019 ENSP00000461429
ENST00000574029 ENSP00000459159
ENST00000576149
ENST00000572259
ENST00000571805 ENSP00000459312
ENST00000571456
ENST00000570650 ENSP00000458651
ENST00000575207
ENST00000570771
ENST00000575100
ENST00000573028 ENSP00000458311
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 15 experimentally validated interaction(s) in this database.
Experimentally validated
Total 15 [view]
Protein-Protein 15 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
Biological Process
GO:0015031 protein transport
GO:0016192 vesicle-mediated transport
Cellular Component
GO:0000938 GARP complex
GO:0010008 endosome membrane
GO:0016020 membrane
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000017288
View Gene Order
ENSBTAG00000018126
Not yet available
Cross-References
SwissProt
TrEMBL I3L0S6 I3L4P9
UniProt Splice Variant
Entrez Gene 55275
UniGene Hs.461819 Hs.594232 Hs.627072 Hs.655880 Hs.691997
RefSeq NM_001128159 NM_018289 XM_005256716 XM_006721554 XM_006721555
HUGO HGNC:25608
OMIM 615850
CCDS CCDS10995 CCDS45558
HPRD 07720
IMGT
EMBL AC015853 AC027455
GenPept
RNA Seq Atlas 55275

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca