Mus musculus Gene: Atp1b4
Summary
InnateDB Gene IDBG-139944.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Atp1b4
Gene Name ATPase, (Na+)/K+ transporting, beta 4 polypeptide
Synonyms 1110020B02Rik
Species Mus musculus
Ensembl Gene ENSMUSG00000016327
Encoded Proteins
ATPase, (Na+)/K+ transporting, beta 4 polypeptide
ATPase, (Na+)/K+ transporting, beta 4 polypeptide
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000101892:
This gene has been found in all vertebrate genomes sequenced to date. However, this gene has undergone a change in function in placental mammals compared to other species. Specifically, in fish, avian, and amphibian species, this gene encodes plasma membrane-bound beta-subunits of Na,K-ATPase. In placental mammals, the encoded protein interacts with the nuclear transcriptional coregulator SKIP and may be involved in the regulation of TGF-beta signaling. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2010]
Gene Information
Type Protein coding
Genomic Location Chromosome X:38316184-38336769
Strand Forward strand
Band A3.3
Transcripts
ENSMUST00000016471 ENSMUSP00000016471
ENSMUST00000115134 ENSMUSP00000110787
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 3 experimentally validated interaction(s) in this database.
Experimentally validated
Total 3 [view]
Protein-Protein 3 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
Biological Process
GO:0006351 transcription, DNA-templated
GO:0006355 regulation of transcription, DNA-templated
GO:0006813 potassium ion transport
GO:0006814 sodium ion transport
Cellular Component
GO:0005634 nucleus
GO:0005637 nuclear inner membrane
GO:0005890 sodium:potassium-exchanging ATPase complex
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
Not yet available
Pathways
NETPATH
REACTOME
KEGG
Cardiac muscle contraction pathway
Aldosterone-regulated sodium reabsorption pathway
Gastric acid secretion pathway
Protein digestion and absorption pathway
Carbohydrate digestion and absorption pathway
Salivary secretion pathway
Bile secretion pathway
Proximal tubule bicarbonate reclamation pathway
Pancreatic secretion pathway
INOH
PID NCI
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
KEGG
Cardiac muscle contraction pathway
Aldosterone-regulated sodium reabsorption pathway
Proximal tubule bicarbonate reclamation pathway
Gastric acid secretion pathway
Pancreatic secretion pathway
Salivary secretion pathway
Bile secretion pathway
Protein digestion and absorption pathway
Carbohydrate digestion and absorption pathway
INOH
PID NCI
Cross-References
SwissProt Q99ME6
TrEMBL B1APX1
UniProt Splice Variant
Entrez Gene 67821
UniGene Mm.60134
RefSeq NM_001290389 XM_006541532 XM_006541533 NM_133690
OMIM
CCDS CCDS72368 CCDS30090
HPRD
IMGT
MGI ID MGI:1915071
MGI Symbol Atp1b4
EMBL AF348324 AF348325 AK053500 AL513347 BC137923 BC137924 CH466570
GenPept AAI37924 AAI37925 AAK30148 AAK30149 BAC35406 CAM25391 EDL29012 EDL29013
RNA Seq Atlas 67821