InnateDB: Systems Biology of the Innate Immune Response

Bos taurus Gene: ATP1B4

Summary

InnateDB Gene

IDBG-629876.3

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

ATP1B4

Gene Name

Protein ATP1B4

Synonyms

Species

Bos taurus

Ensembl Gene

ENSBTAG00000008920

Encoded Proteins

IDBP-681301

Protein ATP1B4

Protein Structure

Useful resources

Stemformatics EHFPI ImmGen

Entrez Gene

Summary

This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000101892:
This gene has been found in all vertebrate genomes sequenced to date. However, this gene has undergone a change in function in placental mammals compared to other species. Specifically, in fish, avian, and amphibian species, this gene encodes plasma membrane-bound beta-subunits of Na,K-ATPase. In placental mammals, the encoded protein interacts with the nuclear transcriptional coregulator SKIP and may be involved in the regulation of TGF-beta signaling. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2010]

Gene Information

Type

Protein coding

Genomic Location

Chromosome X:4919686-4940505

Strand

Reverse strand

Band

Transcripts

ENSBTAT00000011740

ENSBTAP00000011741

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.

Gene Ontology

Molecular Function

Accession	GO Term
GO:0005515	protein binding

Biological Process

GO:0006351	transcription, DNA-templated
GO:0006355	regulation of transcription, DNA-templated
GO:0006813	potassium ion transport
GO:0006814	sodium ion transport

Cellular Component

GO:0005634	nucleus
GO:0005637	nuclear inner membrane
GO:0005890	sodium:potassium-exchanging ATPase complex
GO:0016020	membrane
GO:0016021	integral component of membrane